| Mice harboring the FXN I151F pathological point mutation present decreased frataxin levels, a Friedreich ataxia-like phenotype, and mitochondrial alterations. |
2022 |
Medina Carbonero, M.; Sanz Alcázar, A.; Britti, E.; Delaspre, F.; Cabiscol, E.; Ros, J.; Tamarit, J. |
Article d'investigació |
| Mitochondrial iron and calcium homeostasis in Friedreich ataxia |
2021 |
Tamarit, J.; Britti, E.; Delaspre, F.; Medina Carbonero, M.; Sanz Alcázar, A.; Cabiscol, E.; Ros, J. |
Article d'investigació |
| Calcitriol increases frataxin levels and restores mitochondrial function in cell models of Friedreich Ataxia. |
2021 |
Britti, E.; Delaspre, F.; Sanz-Alcázar, A.; Medina-Carbonero, M.; Llovera, M.; Purroy, R.; Mincheva-Tasheva, S.; Tamarit, J.; Ros, J. |
Article d'investigació |
| Calpain-Inhibitors Protect Frataxin-Deficient Dorsal Root Ganglia Neurons from Loss of Mitochondrial Na+/Ca2+ Exchanger, NCLX, and Apoptosis |
2020 |
Britti, E.; Delaspre, F.; Tamarit, J.; Ros, J. |
Article d'investigació |
| PPAR gamma agonist leriglitazone improves frataxin-loss impairments in cellular and animal models of Friedreich Ataxia. |
2020 |
Rodríguez Pascau, L.; Britti, E.; Calap Quintana, P.; Dong, Y.N.; Vergara, C.; Delaspre, F.; Medina Carbonero, M.; Tamarit, J.; Pallardó, F.V.; Gonzalez Cabo, P.; Ros, J.; Lynch, D.R.; Martinell, M.; |
Article d'investigació |
| Mitochondrial pore opening and loss of Ca2+ exchanger NCLX levels occur after frataxin depletion |
2018 |
Purroy R; Britti E; Delaspre F; Tamarit J; Ros J. |
Article d'investigació |
| Mitochondrial calcium signaling and neurodegenerative diseases |
2018 |
Elena Britti; Fabien Delaspre; Jordi Tamarit; Joaquim Ros. |
Article d'investigació |
| Frataxin-deficient neurons and mice models of Friedreich ataxia are improved by TAT-MTScs-FXN treatment |
2017 |
Britti E, Delaspre F, Feldman A, Osborne M, Greif H, Tamarit J, Ros J. |
Article d'investigació |
| HIF-1α- Targeting Acriflavine Provides Long Term Survival and Radiological Tumor Response in Brain Cancer Therapy |
2017 |
Antonella Mangraviti; Tula Raghavan; Francesco Volpin; Nicolas Skuli; David Gullotti; Jinyuan Zhou; Laura Asnaghi; Eric Sankey; Ann Liu; Yuan Wang; Dong-Hoon Lee; Noah Gorelick; Riccardo Serra; Michae |
Article d'investigació |
| Sox9b is a mediator of retinoic acid signaling restricting endocrine progenitor differentiation |
2016 |
Wei Huang; Rebecca L. Beer; Fabien Delaspre; Guangliang Wang; Hannah E. Edelman; Hyewon Park; Mizuki Azuma; Michael J. Parsons |
Article d'investigació |
| Centroacinar cells are progenitors that contribute to endocrine pancreas regeneration |
2015 |
Fabien Delaspre, Rebecca L. Beer, Meritxell Rovira, Wei Huang, Guangliang Wang, Stephen Gee, Maria del Carmen Vitery, Sarah J. Wheelan, and Michael J. Parsons |
Article d'investigació |
| First quantitative high-throughput screen in zebrafish identifies novel pathways for increasing pancreatic β-cell mass |
2015 |
Guangliang Wang, Surendra K. Rajpurohit, Fabien Delaspre, Steven L. Walker, David T. White, Alexis Ceasrine, Rejji Kuruvilla, Ruo-jing Li, Joong S. Shim, Jun O. Liu, Michael J. Parsons, Jeff S. Mumm |
Article d'investigació |
| Retinoic acid plays an evolutionarily conserved and biphasic role in pancreas development |
2014 |
Wei Huang, Guangliang Wang, Fabien Delaspre, Vitery MdC, Rebecca Beer, Michael J. Parsons |
Article d'investigació |
| Directed pancreatic acinar differentiation of mouse embryonic stem cells via embryonic signalling molecules and exocrine transcription factors |
2013 |
Fabien Delaspre, Mohammad Massumi, Marta Salido, Bernat Soria, Philippe Ravassard, Pierre Savatier, Anouchka Skoudy |
Article d'investigació |
| Murine Embryonic Stem Cell-Derived Pancreatic Acinar Cells Recapitulate Features of Early Pancreatic Differentiation |
2008 |
Meritxell Rovira, Fabien Delaspre, Mohammad Massumi, Selma A. Serra, Miguel Angel Valverde, Pierre Savatier, Josep Lloreta, Marlène Dufresne, Bruno Payré, Stephen F. Konieczny, Francisco X. Real, Anou |
Article d'investigació |
| The Ralstonia solanacearum pathogenicity regulator HrpB induces 3-hydroxy-oxindole synthesis |
2007 |
Fabien Delaspre, Carlos G. Nieto Peñalver, Olivier Saurel, Patrick Kiefer, Emmanuel Gras, Alain Milon, Christian Boucher, Stéphane Genin, Julia A. Vorholt |
Article d'investigació |
