| A motor neuron disease mouse model reveals a non-canonical profile of senescence biomarkers. |
2022 |
Torres, P.; Anerillas, C.; Ramírez Núñez, O.; Fernàndez, A.; Encinas, M.; Povedano, M.; Andrés Benito, P.; Ferrer, I.; Ayala, V.; Pamplona, R.; Portero Otín, M. |
Article d'investigació |
| Metabolomic Analysis Points to Bioactive Lipid Species and Acireductone Dioxygenase 1 (ADI1) as Potential Therapeutic Targets in Poor Prognosis Endometrial Cancer |
2022 |
Gatius, S.; Jove, M.; Megino Luque, C.; Albertí Valls, M.; Yeramian, A.; Bonifaci, N.; Piñol, M.; Santacana, M.; Pradas, I.; Llobet Navas, D.; Pamplona, R.; Matías Guiu, X.; Eritja, N. |
Article d'investigació |
| Blood-based lipidomic signature of severe obstructive sleep apnoea in Alzheimer's disease. |
2022 |
Dakterzada, F.; Benítez, I.D.; Targa, A.; Carnes, A., Pujol, M.; Jové, M.; Mínguez, O., Vaca, R., Sánchez de la Torre, M.; Barbé, F.; Pamplona, R.; Piñol Ripoll, G. |
Article d'investigació |
| The causal role of lipoxidative damage in mitochondrial bioenergetic dysfunction linked to Alzheimer's disease pathology. |
2022 |
Jove, M.; Mota Martorell, N.; Torres, P.; Ayala, V.; Portero Otin, M.; Ferrer, I.; Pamplona, R. |
Capítol de llibre docent |
| mTORC1 and Nutritional Interventions in Ageing |
2022 |
Mota Martorell, N.; Jove, M.; Pamplona, R. |
Capítol de llibre docent |
| Role of mTOR Complex 1 in Longevity. |
2022 |
Mota Martorell, N.; Jové, M.; Pamplona, R. |
Capítol de llibre docent |
| Prevalence of Obstructive Sleep Apnoea and Its Association With Atherosclerotic Plaques in a Cohort of Subjects With Mild-Moderate Cardiovascular Risk |
2022 |
Sapiña Beltrán, E.; Gracia Lavedan, E.; Torres, G.; Gaeta, A.M.; Paredes, J.; Mayoral, A.; Fernández, E.; Bermúdez López, M.; Valdivielso, J.M.; Farràs Salles, C.; Pamplona, R.; Lecube, A.; de Batlle, |
Article d'investigació |
| Weak Association between Skin Autofluorescence Levels and Prediabetes with an ILERVAS Cross-Sectional Study. |
2022 |
Sánchez, E.; Kerkeni, M.; Hernández, M.; Gavaldà, R.; Rius, F.; Sauret, A.; Torres, G.; Bermúdez López, M.; Fernández, E.; Castro Boqué, E.; Purroy, F.; Mauricio, D.; Farràs Sallés, C.; Buti, M.; Godo |
Article d'investigació |
| Prediabetes Is Associated with Increased Prevalence of Sleep-Disordered Breathing |
2022 |
Sánchez, E.; Sapiña Beltrán, E.; Gavaldà, R.; Barbé, F.; Torres, G.; Sauret, A.; Dalmases, M.; López Cano, C.; Gutiérrez Carrasquilla, L.; Bermúdez López, M.; Fernández, E.; Purroy, F.; Castro Boqué, |
Article d'investigació |
| Modulation of mitochondrial and inflammatory homeostasis through RIP140 is neuroprotective in an adrenoleukodystrophy mouse model. |
2022 |
Ranea-Robles P; Galino J; Espinosa L; Schlüter A; Ruiz M; Calingasan NY; Villarroya F; Naudí A; Pamplona R; Ferrer I; Beal MF; Portero-Otín M; Fourcade S; Pujol A. |
Article d'investigació |
| Lung function impairment is related to subclinical atherosclerosis only in active smokers. |
2022 |
Gonzalez, J.; Gracia Lavedan, E.; Gomez, S.; Barril, S.; Godoy, P.; Bermudez Lopez, M.; Betriu, A.; Fernandez, E.; Lecube, A.; Pamplona, R.; Purroy, F.; Farras, C.; Barbe, F.; Torres, G.; de Batlle, J |
Article d'investigació |
| mTOR Complex 1 Content and Regulation Is Adapted to Animal Longevity. |
2022 |
Mota Martorell, N.; Jové, M.; Pamplona, R. |
Review |
| Response to Dr. Buschard and Colleagues' Letter to the Editor: Sulfatide and Longevity. |
2022 |
Jové, M.; Pamplona, R. |
Article d'investigació |
| Presence of Blastocystis in gut microbiota is associated with cognitive traits and decreased executive function. |
2022 |
Mayneris Perxachs, J.; Arnoriaga Rodríguez, M.; Garre Olmo, J.; Puig, J.; Ramos, R.; Trelis, M.; Burokas, A.; Coll, C.; Zapata Tona, C.; Pedraza, S.; Pérez Brocal, V.; Ramió, L.; Ricart, W.; Moya, A.; |
Article d'investigació |
| DPP9 as a Potential Novel Mediator in Gastrointestinal Virus Infection. |
2022 |
Del Castillo Izquierdo, Á.; Moreno Navarrete, J.M.; Latorre, J.; Arnoriaga Rodríguez, M.; Ballanti, M.; Monteleone, G.; Alessandro Paoluzi, O.; Mingrone, G.; Puig, J.; Ramos, R.; Garre Olmo, J.; Jové, |
Article d'investigació |
| Genistein effect on cognition in prodromal Alzheimer's disease patients. The GENIAL clinical trial. |
2022 |
Viña, J.; Escudero, J.; Baquero, M.; Cebrián, M.; Carbonell Asíns, J.A.; Muñoz, J.E.; Satorres, E.; Meléndez, J.C.; Ferrer Rebolleda, J.; Cózar Santiago, M.D.P.; Santabárbara Gómez, J.M.; Jové, M.; Pa |
Article d'investigació |
| Ischemia preconditioning induces an adaptive response that defines a circulating metabolomic signature in ischemic stroke patients. |
2022 |
Sol, J.; Colàs Campàs, L.; Mauri Capdevila, G.; Molina Seguin, J.; Galo Licona, J.D.; Torres Querol, C.; Aymerich, N.; Ois, Á.; Roquer, J.; Tur, S.; García Carreira, M.D.C.; Martí Fàbregas, J.; Cruz C |
Article d'investigació |
| Elovl2-Ablation Leads to Mitochondrial Membrane Fatty Acid Remodeling and Reduced Efficiency in Mouse Liver Mitochondria. |
2022 |
Gómez Rodríguez, A.; Talamonti, E.; Naudi, A.; Kalinovich, A.V.; Pauter, A.M.; Barja, G.; Bengtsson, T.; Jacobsson, A.; Pamplona, R.; Shabalina, I.G. |
Article d'investigació |
| Long-lived Humans Have a Unique Plasma Sphingolipidome. |
2022 |
Pradas, I.; Jové, M.; Huynh, K.; Ingles, M.; Borras, C.; Mota Martorell, N.; Galo Licona, J.D.; Puig, J.; Viña, J.; Meikle, P.J.; Pamplona, R. |
Article d'investigació |
| Selective brain regional changes in lipid profile with human aging. |
2022 |
Mota Martorell, N.; Andrés Benito, P.; Martín Gari, M.; Galo Licona, J.D.; Sol, J.; Fernández Bernal, A.; Portero Otín, M.; Ferrer, I.; Jove, M.; Pamplona, R. |
Article d'investigació |
| Microbiota alterations in proline metabolism impact depression. |
2022 |
Mayneris Perxachs, J.; Castells Nobau, A.; Arnoriaga Rodríguez, M.; Martin, M.; de la Vega Correa, L.; Zapata, C.; Burokas, A.; Blasco, G.; Coll, C.; Escrichs, A.; Biarnés, C.; Moreno Navarrete, J.M.; |
Article d'investigació |
| Development and Validation of a Personalized, Sex-Specific Prediction Algorithm of Severe Atheromatosis in Middle-Aged Asymptomatic Individuals: The ILERVAS Study. |
2022 |
Bermúdez López, M.; Martí Antonio, M.; Castro Boqué, E.; Bretones, M.D.M.; Farràs, C.; Torres, G.; Pamplona, R.; Lecube, A.; Mauricio, D.; Valdivielso, J.M.; Fernández, E. |
Article d'investigació |
| Activating cannabinoid receptor 2 preserves axonal health through GSK-3β/NRF2 axis in adrenoleukodystrophy. |
2022 |
Parameswaran, J.; Goicoechea, L.; Planas Serra, L.; Pastor, A.; Ruiz, M.; Calingasan, N.Y.; Guilera, C.; Aso, E.; Boada, J.; Pamplona, R.; Portero Otín, M.; de la Torre, R.; Ferrer, I.; Casasnovas, C. |
Article d'investigació |
| Methionine Metabolism Is Down-Regulated in Heart of Long-Lived Mammals |
2022 |
Mota Martorell, N.; Jové, M.; Berdún, R.; Òbis, È.; Barja, G.; Pamplona, R. |
Article d'investigació |
| Metabolomics reveals that fittest trail runners show a better adaptation of bioenergetic pathways |
2022 |
Puigarnau, S.; Fernandez, A.; Obis, E.; Jové, M.; Castañer; M.; Pamplona, R.; Portero-Otin, M.; Camerino, O. |
Article d'investigació |
| Lipoxidation: features, neurological tissues, and aging |
2021 |
Pamplona R; Jove M; Pradas I; Mota-Martorell N; Ferrer I. |
Capítol de llibre docent |
| The Causal Role of Lipoxidative Damage in Mitochondrial Bioenergetic Dysfunction Linked to Alzheimer's Disease Pathology |
2021 |
Jové, M.; Mota Martorell, N.; Torres, P.; Ayala, V.; Portero Otin, M.; Ferrer, I.; Pamplona, R. |
Review |
| Subjects with detectable Saccharomyces cerevisiae in the gut microbiota show deficits in attention and executive function |
2021 |
Arnoriaga Rodríguez, M.; Mayneris Perxachs, J.; Coll, C.; Pérez Brocal, V.; Ricart, W.; Moya, A.; Ramió Torrentà, L.; Pamplona, R.; Jové, M.; Portero Otin, M.; Fernández Real, J.M. |
Article d'investigació |
| New insights into human prefrontal cortex aging with a lipidomics approach |
2021 |
Jové, M.; Mota Martorell, N.; Torres, P.; Portero Otin, M.; Ferrer, I.; Pamplona, R. |
Article d'investigació |
| Lipidomic traits of plasma and cerebrospinal fluid in amyotrophic lateral sclerosis correlate with disease progression |
2021 |
Sol, J.; Jové, M.; Povedano, M.; Sproviero, W.; Domínguez, R.; Piñol Ripoll, G.; Romero Guevara, R.; Hye, A.; Al Chalabi, A.; Torres, P.; Andres Benito, P.; Area Gómez, E.; Pamplona, R.; Ferrer, I.; A |
Article d'investigació |
| Cell Stress Induces Mislocalization of Transcription Factors with Mitochondrial Enrichment |
2021 |
Rossi, C.; Fernàndez, A.; Torres, P.; Ramirez Nuñez, O.; Granado Serrano, A.B.; Fontdevila, L.; Povedano, M.; Pamplona, R.; Ferrer, I.; Portero Otin, M. |
Article d'investigació |
| Plasma profiling reveals a blood-based metabolic fingerprint of obstructive sleep apnea |
2021 |
Pinilla, L.; Benítez, I.D.; Santamaria Martos, F.; Targa. A.; Moncusí Moix, A.; Dalmases. M.; Mínguez, O.; Aguilà, M.; Jové, M.; Sol, J.; Pamplona, R.; Barbé, F.; Sánchez de la Torre, M. |
Article d'investigació |
| Age-Related Changes in Lipidome of Rat Frontal Cortex and Cerebellum Are Partially Reversed by Methionine Restriction Applied in Old Age |
2021 |
Jové, M.; Cabré, R.; Mota Martorell, N.; Martin Garí, M.; Obis, È.; Ramos, P.; Canales, I.; Galo Licona, J.D.; Sol, J.; Nogueras, L.; Torres, P.; Portero Otín, M.; Ayala, V.; Ferrer, I.; Pamplona, R. |
Article d'investigació |
| Lifelong soya consumption in males does not increase lifespan but increases health span under a metabolic stress such as type 2 diabetes mellitus |
2021 |
Borrás, C.; Abdelaziz, K.M.; Díaz, A.; Gambini, J.; Jové, M.; López Grueso, R.; Mas Bargues, C.; Monleón, D.; Pamplona, R.; Viña, J. |
Article d'investigació |
| Dysregulated protein phosphorylation: A determining condition in the continuum of brain aging and Alzheimer's disease |
2021 |
Ferrer, I.; Andrés Benito, P.; Ausín, K.; Pamplona, R.; Del Rio, J.A.; Fernández Irigoyen, J.; Santamaría, E. |
Article d'investigació |
| Up-Regulation of Specific Bioactive Lipids in Celiac Disease |
2021 |
Martín Masot, R.; Galo Licona, J.D.; Mota Martorell, N.; Sol, J.; Jové, M.; Maldonado, J.; Pamplona, R.; Nestares, T. |
Article d'investigació |
| mTORC1 is also involved in longevity between species |
2021 |
Barja, G.; Pamplona, R. |
Article d'investigació |
| Plasma methionine metabolic profile is associated with longevity in mammals |
2021 |
Mota Martorell, N.; Jové, M.; Berdún, R.; Pamplona, R. |
Article d'investigació |
| Prevalence and Predictors of Cerebral Microangiopathy Determined by Pulsatility Index in an Asymptomatic Population From the ILERVAS Project |
2021 |
Purroy, F.; Sánchez, E.; Lecube, A.; Arqué, G.; Vicente Pascual, M.; Mauri Capdevila, G.; Torreguitart, N.; Hernández, M.; Barbé, F.; Fernández, E.; Pamplona, R.; Farràs, C.; Mauricio, D.; Bermúdez Ló |
Article d'investigació |
| Subclinical atheromatosis localization and burden in a low-to-moderate cardiovascular risk population: the ILERVAS study |
2021 |
Bermudez Lopez; M. Martinez Alonso; M. Castro Boque; E. Betriu; A. Cambray; S. Farras; C. Barbe; F. Pamplona; R. Lecube; A. Mauricio; D. Purroy; F. Valdivielso; J. M. Fernandez; E. |
Article d'investigació |
| Decrease in sleep depth is associated with higher cerebrospinal fluid neurofilament light levels in patients with Alzheimer's disease |
2021 |
Targa, A.; Dakterzada, F.; Benítez, I.; López, R.; Pujol, M.; Dalmases, M.; Arias, A.; Sánchez de la Torre, M.; Zettenberg, H.; Blennow, K.; Pamplona, R.; Jové, M.; Barbé, F.; Piñol-Ripoll, G. |
Article d'investigació |
| Clinical Usefulness of Anthropometric Indices to Predict the Presence of Prediabetes. Data from the ILERVAS Cohort |
2021 |
Sánchez, M.; Sánchez, E.; Bermúdez López, M.; Torres, G.; Farràs Sallés, C.; Pamplona, R.; Castro Boqué, E.; Valdivielso, J.M.; Purroy, F.; Martínez Alonso, M.; Godoy, P.; Mauricio, D.; Fernández, E.; |
Article d'investigació |
| Is the NDUFV2 subunit of the hydrophilic complex I domain a key determinant of animal longevity? |
2021 |
Pamplona, R.; Jove, M.; Mota Martorell, N.; Barja, G. |
Article d'investigació |
| Obesity-associated deficits in inhibitory control are phenocopied to mice through gut microbiota changes in one-carbon and aromatic amino acids metabolic pathways. |
2021 |
Arnoriaga Rodríguez, M.; Mayneris Perxachs, J.; Contreras Rodriguez, O.; Burokas, A.; Blasco, G.; Coll, C.; Biarnes, C.; Castells Nobau, A.; Puig, J.; Garre, J.; Ramos, R.; Pedraza, S.; Brugada, R.; V |
Article d'investigació |
| Methionine transsulfuration pathway is upregulated in long-lived humans. |
2021 |
Mota Martorell, N.; Jove, M.; Borras, C.; Berdun, R.; Obis, E.; Sol, J.; Cabre, R.; Pradas, I.; Galo Licona, J.D.; Puig, J.; Viña, J.; Pamplona, R. |
Article d'investigació |
| Nuclear lipidome is altered in amyotrophic lateral sclerosis: A pilot study |
2021 |
Ramírez Nuñez, O.; Jové, M.; Torres, P.; Sol, J.; Fontdevila, L.; Romero Guevara, R.; Andrés Benito, P.; Ayala, V.; Rossi, C.; Boada, J.; Povedano, M.; Ferrer, I.; Pamplona, R.; Portero Otin, M. |
Article d'investigació |
| Protein succination as a potential surrogate biomarker of airway obstruction. The ilervas project. |
2020 |
J. González; E. Gracia Lavedan; R. Pamplona; E. Fernández; A. Lecube; J. P. de Torres; F. Barbé; G. Torres; ILERVAS Study Group. |
Article d'investigació |
| Estrés oxidativo, envejecimiento y longevidad. |
2020 |
Jove, M.; Pradas, I.; Pamplona, R.. |
Capítol de llibre docent |
| Selected cryptic exons accumulate in hippocampal cell nuclei in Alzheimer's disease with and without associated TDP-43 proteinopathy |
2020 |
Torres, P.; Andrés Benito, P.; Fernàndez Bernal, A.; Ricart, M.; Ayala, V.; Pamplona, R.; Ferrer, I.; Portero Otin, M. |
Article d'investigació |
| Metabolic adaptations in spontaneously immortalized PGC-1α knock-out mouse embryonic fibroblasts increase their oncogenic potential |
2020 |
Prieto, I.; Alarcón, CR.; García-Gómez, R.; Berdún, R.; Urgel, T.; Portero, M.; Pamplona, R.; Martínez-Ruiz, A.; Ruiz-Sanz, JI.; Ruiz-Larrea, MB.; Jove, M.; Cerdán, S.; Monsalve, M. |
Article d'investigació |
| Dietary intervention reverses fatty liver and altered gut microbiota during early-life undernutrition. |
2020 |
Bauer, K.C.; Huus, K.E.; Brown, E.M.; Bozorgmehr, T.; Petersen, .CN.; Cirstea, M.S.; Woodward, S.E.; McCoy, J.; Hun, J.; Pamplona, R.; Ayala, V.; Finlay, B.B. |
Article d'investigació |
| Obesity impairs short-term and working memory through gut microbial metabolism of aromatic amino acids. |
2020 |
Arnoriaga-Rodríguez M; Mayneris-Perxachs J; Burokas A; Contreras-Rodríguez O; Blasco G; Coll C; Biarnés C; Miranda-Olivos R; Latorre J; Moreno-Navarrete JM; Castells-Nobau A; Sabater M; Palomo-Buitrag |
Article d'investigació |
| Confirmation of the cardioprotective effect of MitoGamide in the diabetic heart. |
2020 |
Park M; Nishimura T; Baeza-Garza CD; Caldwell ST; Boon Li Pun P; Prag HA; Young T; Sauchanka O; Logan A; Forkink M; Gruszczyk AV; Prime TA; Arndt S; Naudi A; Pamplona R; Coughlan MT; Tate M; Ritchie R |
Article d'investigació |
| The lipidome fingerprint of longevity. |
2020 |
Jove, M.; Mota-Martorell, N.; Pradas, I.; Galo-Licona, J.D.; Martin-Gari, M.; Obis, E.; Sol, J.; Pamplona, R. |
Review |
| The advanced lipoxidation end-product malondialdehyde-lysine in aging and longevity. |
2020 |
Jove, M.; Mota-Martorell, N.; Pradas, I.; Martin-Gari, M.; Ayala, V.; Pamplona, R. |
Review |
| Alterations in one-carbon metabolism in celiac disease. |
2020 |
Martin-Masot, R.; Mota-Martorell, N.; Jove, M.; Maldonado, J.; Pamplona, R.; Nestares, T. |
Article d'investigació |
| Whole-Brain Dynamics in Aging: Disruptions in Functional Connectivity and the Role of the Rich Club |
2020 |
Escrichs, A.; Biarnes, C.; Garre Olmo, J.; Fernandez Real, J.M.; Ramos, R.; Pamplona, R.; Brugada, R.; Serena, J.; Ramio Torrenta, L.; Coll de Tuero, G.; Gallart, L.; Barretina, J.; Vilanova, J.C.; Ma |
Article d'investigació |
| Lipid alterations in human frontal cortex in ALS-FTLD-TDP43 proteinopathy spectrum are partially related to peroxisome impairment |
2020 |
Andres Benito, P.; Gelpi, E.; Jove, M.; Mota Martorell, N.; Obis, E.; Portero Otin, M.; Povedano, M.; Pujol, A.; Pamplona, R.; Ferrer, I. |
Article d'investigació |
| Gene expression and regulatory factors of the mechanistic target of rapamycin (mTOR) complex 1 predict mammalian longevity |
2020 |
Mota Martorell, N.; Jove, M.; Pradas, I.; Berdún, R.; Sanchez, I.; Naudi, A.; Gari, E.; Barja, G.; Pamplona, R. |
Article d'investigació |
| Succination of protein thiols in human brain aging. |
2020 |
Jove, M.; Pradas, I.; Mota-Martorell, N.; Cabre, R.; Ayala, V.; Ferrer, I.; Pamplona, R. |
Article d'investigació |
| Low abundance of NDUFV2 and NDUFS4 subunits of the hydrophilic complex I domain and VDAC1 predicts mammalian maximum longevity. |
2020 |
Mota-Martorell, N.; Jove, M.; Pradas, I.; Sanchez, I.; Gomez, J.; Naudi, A.; Barja, G.; Pamplona, R. |
Article d'investigació |
| Mediterranean diet, physical activity and subcutaneous advanced glycation end products accumulation: a cross-sectional analysis in The ILERVAS project |
2020 |
Sánchez, E.; Betriu, À.; Salas Salvadó, J.; Pamplona, R.; Barbé, F.; Purroy, F.; Farràs, C.; Fernández, E.; López Cano, C.; Mizab, C.; Lecube, A. |
Article d'investigació |
| Gender-specific beneficial effects of docosahexaenoic acid dietary supplementation in G93A-SOD1 amyotrophic lateral sclerosis mice |
2020 |
Torres P; Cacabelos D; Pairada J; Bauer KC; Boada J; Fontdevila L; Rossi C; Povedano M; Ferrer I; Pamplona R; Finlay BB; Portero-Otín M; Ayala V |
Article d'investigació |
| Lipidomic profiling identifies signatures of metabolic risk. |
2020 |
Yin, X.; Willinger, C.M.; Keefe, J.; Liu, J.; Fernández Ortiz, A.; Ibáñez, B.; Peñalvo, J.; Adourian, A.; Chen, G.; Corella, D.; Pamplona, R.; Portero Otin, M.; Jove, M.; Courchesne, P.; van Duijn, C. |
Article d'investigació |
| Are obesity indices useful for detecting subclinical atheromatosis in a middle-age population? |
2020 |
Sánchez, E.; Sánchez, M., Betriu, À.; Rius, F.; Torres, G.; Purroy, F.; Pamplona, R.; Ortega, M.; López Cano, C.; Hernández, M.; Bueno, M.; Fernández, E.; Salvador, J.; Lecube, A. |
Article d'investigació |
| Molecular phenomics of a high-calorie diet-induced porcine model of prepubertal obesity |
2020 |
Jov,é M.; Tibau, J.; Serrano, JC.; Berdún, R.; Rodríguez Palmero, M.; Font-I-Furnols, M.; Cassanyé, A.; Rodriguez Mortera, R.; Sol, J.; Rassendren, H.; Fàbrega, E:; Crescenti, A.; Castell, A.; Sabater |
Article d'investigació |
| The Aging Imageomics Study: rationale, design and baseline characteristics of the study populatio |
2020 |
Puig J, Biarnes C, Pedraza S, Vilanova JC, Pamplona R, Fernández-Real JM, Brugada R, Ramos R, Coll-de-Tuero G, Calvo-Perxas L, Serena J, Ramió-Torrentà L, Gich J, Gallart L, Portero-Otin M, Alberich-B |
Article d'investigació |
| Impairment of mitochondrial redox status in peripheral lymphocytes of multiple sclerosis patients |
2019 |
Gonzalo H; Nogueras L; Gil-Sánchez A; Hervás JV; Valcheva P; González-Mingot C; Martin-Gari M; Canudes M; Peralta S; Solana MJ; Pamplona R; Portero-Otin M; Boada J; Serrano JCE; Brieva L |
Article d'investigació |
| A prospective pilot study using metabolomics discloses specific fatty acid, catecholamine and tryptophan metabolic pathways as possible predictors for a negative outcome after severe trauma |
2019 |
Servià L.; Jové M.; Sol J.; Pamplona R.; Badia M.; Montserrat N.; Portero-Otin M.; Trujillano J. |
Article d'investigació |
| Subcutaneous advanced glycation end-products and lung function according to glucose abnormalities: The ILERVAS project. |
2019 |
Sánchez, E.; Lecube, A.; Betriu, A.; Hernández, C.; López Cano, C.; Gutiérrez Carrasquilla, L.; Kerkeni, M.; Yeramian, A.; Purroy, F.; Pamplona, R.; Farràs, C.; Fernández, E.; Barbé, F.; Simó, R. |
Article d'investigació |
| Effects of aging and methionine restriction on rat kidney metabolome. |
2019 |
Pradas I; Jove M; Cabre R; Ayala V; Mota-Martorell N; Pamplona R. |
Article d'investigació |
| Metformin induces lipid changes on sphingolipid species and oxidized lipids in polycystic ovary syndrome women. |
2019 |
Pradas I; Rovira-Llopis S; Naudi A; Bañuls C; Rocha M; Hernandez-Mijares A; Pamplona R; Victor VM; Jove M. |
Article d'investigació |
| Manipulating mtDNA in vivo reprograms metabolism via novel response mechanisms. |
2019 |
Bahhir D; Yalgin C; Ots L; Järvinen S; George J; Naudí A; Krama T; Krams I; Tamm M; Andjelković A; Dufour E; Gonzales de Cosar J; Gerards M; Parhiala M; Pamplona R; Jacobs HT; Jõers P. |
Article d'investigació |
| Lipid profile of cerebrospinal fluid in multiple sclerosis patients: a potential tool for diagnosis. |
2019 |
Nogueras L; Gonzalo H; Jové M; Sol J; Gil-Sanchez A; Hervás JV; Valcheva P; Gonzalez-Mingot C; Solana MJ; Peralta S; Pamplona R; Brieva L. |
Article d'investigació |
| Deficient endoplasmic reticulum-mitochondrial phosphatidylserine transfer causes liver disease. |
2019 |
Hernandez-Alvarez MI; Sebastian D; Vives S; Ivanova S; Bartoccioni P; Kakimoto P; Plana N; Veiga SR; Hernandez V; Vasconcelos N; Gopalacharyulu P; Adrover A; Jove M; Pamplona R; Berenguer-Llergo A; Go |
Article d'investigació |
| Biosynthesis de novo of glycerophospholipids and longevity. |
2019 |
Mota-Martorell N; Pradas I; Jove M; Naudi A; Pamplona R. |
Article d'investigació |
| The cirrhotic liver is depleted of docosahexaenoic acid (DHA), a key modulator of NF-κB and TGFβ pathways in hepatic stellate cells. |
2019 |
Enguita M; Razquin N; Pamplona R; Quiroga J; Prieto J; Fortes P. |
Article d'investigació |
| Biomarker identification, safety and efficacy of high-dose antioxidants for adrenomyeloneuropathy: a phase II pilot study. |
2019 |
Casasnovas C; Ruiz M; Schlüter A; Naudi A; Fourcade S; Veciana M; Castañer S; Alberti A; Johnson M; Raymond G; Fatemi A; Moser AB; Villarroya F; Portero-Otin M; Artuch R; Pamplona R; Pujol A. |
Article d'investigació |
| Redox lipidomics to better understand brain aging and function. |
2019 |
Pamplona R; Borras C; Jove M; Pradas I; Ferrer I; Viña J. |
Article d'investigació |
| Dissimilar Impact of a Mediterranean Diet and Physical Activity on Anthropometric Indices: A Cross-Sectional Study from the ILERVAS Project |
2019 |
Sánchez, M.; Sánchez, E.; Hernández, M.; Barril, S.; Purroy, F.; Rius, F.; Pamplona, R.; Farràs-Sallés, C.; Gutiérrez Carrasquilla, L.; Fernández, E.; Bermúdez-López, M.; Salvador, J.; Salas-Salvadó, |
Article d'investigació |
| Exceptional human longevity is associated with a specific plasma phenotype of ether lipids. |
2019 |
Pradas, I.; Jové, M.; Huynh, K.; Puig, J.; Ingles, M.; Borras, C.; Viña, J.; Meikle, P.J.; Pamplona, R. |
Article d'investigació |
| Essential physiological differences characterise short- and long-lived strains of Drosophila melanogaster |
2019 |
Gubina N, Naudi A, Stefanatos R, Jove M, Scialo F, Fernandez-Ayala DJ, Rantapero T, Yurkevych I, Portero-Otin M, Nykter M, Lushchak O, Navas P, Pamplona R, Sanz A. |
Article d'investigació |
| Skin Autofluorescence Measurement in Subclinical Atheromatous Disease: Results from the ILERVAS Project. |
2019 |
Sánchez, E.; Betriu, À.; Yeramian, A.; Fernández, E.; Purroy, F.; Sánchez de la Torre, M.; Pamplona, R.; Miquel, E.; Kerkeni, M.; Hernández, C.; Simó, R.; Lecube, A.; Hernández, M.; Rius, F.; Polanco, |
Article d'investigació |
| Effects of mediterranean diet and physical activity on pulmonary function: a cross-sectional analysis in the ILERVAS project. |
2019 |
Gutiérrez Carrasquilla, L.; Sánchez, E.; Hernández, M.; Polanco, D.; Salas-Salvadó, J.; Betriu, À.; Gaeta, AM.; Carmona, P.; Purroy, F.; Pamplona, R.; Farràs, C.; López-Cano, C.; Fernández, E.; Lecube |
Article d'investigació |
| Lipids and lipoxidation in human brain aging. Mitochondrial ATP-synthase as a key lipoxidation target. |
2019 |
Jové, M; Pradas, I; Dominguez-Gonzalez, M; Ferrer, I; Pamplona, R. |
Article d'investigació |
| Lung function measurements in the prediabetes stage: data from the ILERVAS Project |
2019 |
Sánchez E.; Gutiérrez Carrasquilla, L.; Barbé F.; Betriu À, López Cano, C.; Gaeta AM.; Purroy F.; Pamplona R.; Ortega M.; Fernández E.; Hernández C.; Lecube A.; Simó R. |
Article d'investigació |
| Characteristics of atheromatosis in the prediabetes stage: a cross-sectional investigation of the Ilervas project. |
2019 |
Sanchez, E.; Betriu, A.; Lopez Cano, C.; Fernandez, E.; Purroy, F.; Farras, C.; Barbe, F.; Pamplona, R.; Hernandez, C.; Simo, R.; Lecube, A. |
Article d'investigació |
| Cryptic exon splicing function of TARDBP interacts with autophagy in nervous tissue. |
2018 |
Torres, P.; Ramírez-Núñez, O.; Romero-Guevara, R.; Barés, G.; Granado-Serrano, A.B.; Ayala, V.; Boada, J.; Fontdevila, L.; Povedano, M.; Sanchís, D.; Pamplona, R.; Ferrer, I.; Portero-Otín, M. |
Article d'investigació |
| Aberrant regulation of the GSK-3 beta/NRF2 axis unveils a novel therapy for adrenoleukodystrophy |
2018 |
Ranea-Robles P; Launay N; Ruiz M; Calingasan NY; Dumont M; Naudí A; Portero-Otín M; Pamplona R; Ferrer I; Beal MF; Fourcade S; Pujol A. |
Article d'investigació |
| Location-dependent effects of trauma on oxidative stress in humans |
2018 |
Servia, L.; Serrano JCE.; Pamplona, R.; Badia, M.; Montserrat, N.; Portero-Otin, M.; Trujillano, J. |
Article d'investigació |
| Lipidomics Reveals a Tissue-Specific Fingerprint |
2018 |
Pradas I; Huynh K; Cabré R; Ayala V; Meikle PJ; Jové M; Pamplona R. |
Article d'investigació |
| Lipidomics reveals altered biosynthetic pathways of glycerophospholipids and cell signaling as biomarkers of the polycystic ovary syndrome. |
2018 |
Jové M; Pradas I; Naudí A; Rovira-Llopis S; Bañuls C; Rocha M; Portero-Otin M; Hernández-Mijares A; Victor VM; Pamplona R. |
Article d'investigació |
| Regional vulnerability to lipoxidative damage and inflammation in normal human brain aging |
2018 |
Domínguez-González M, Puigpinós M, Jové M, Naudi A, Portero-Otín M, Pamplona R, Ferrer I. |
Article d'investigació |
| Generation and quality control of lipidomics data for the alzheimer's disease neuroimaging initiative cohort. |
2018 |
Barupal DK; Fan S; Wancewicz B; Cajka T; Sa M; Showalter MR; Baillie R; Tenenbaum JD; Louie G; Alzheimer's Disease Neuroimaging Initiative; Alzheimer's Disease Metabolomics Consortium; Kaddurah-Daouk |
Article d'investigació |
| Lipid profile in human frontal cortex is sustained throughout healthy adult lifespan to decay at advanced ages |
2018 |
Cabré R; Naudí A; Dominguez-Gonzalez M; Jové M; Ayala V; Mota-Martorell N; Pradas I; Nogueras L; Rué M; Portero-Otín M; Ferrer I; Pamplona R |
Article d'investigació |
| Differential metabolic profiles associated to movement behaviour of stream-resident brown trout (Salmo trutta) |
2017 |
Oromi N; , Jové M; Pascual-Pons M; Royo JL; Rocaspana R; Aparicio E; Pamplona R; Palau A; Sanuy D; Fibla J, Portero-Otin M |
Article d'investigació |
| Tumour-microenvironmental blood flow determines a metabolomic signature identifying lysophospholipids and resolvin D as biomarkers in endometrial cancer patients. |
2017 |
Eritja N; Jove M; Eldevik Fasmer K; Gatius S; Portero-Otin M; Trovik J; Krakstad C; Sol J; Pamplona R; Haldorsen IS; Matias-Guiu X. |
Article d'investigació |
| Nontargeted brain lipidomic profiling performed by UPLC-ESI-qTOF-MS/MS. |
2017 |
Naudi A; Cabré R; Jové M; Pamplona R. |
Capítol de llibre docent |
| Specific metabolomics adaptations define a differential regional vulnerability in the human cerebral cortex. |
2017 |
Cabré R; Jové M; Naudí A; Ayala V; Piñol-Ripoll G; Gil-Villar MP; Dominguez-Gonzalez M; Obis E; Berdun R; Mota-Martorell N; Portero-Otin M; Ferrer I: Pamplona R. |
Capítol de llibre docent |
| Membrane lipid unsaturation as physiological adaption to animal longevity. |
2017 |
Naudí A, Jové M, Ayala V, Portero-Otin M, Barja G, Pamplona R. |
Capítol de llibre docent |
| Loss of SIRT2 leads to axonal degeneration and locomotor disability associated with redox and energy imbalance. |
2017 |
Fourcade S; Morato L; Parameswaran J; Ruiz M; Ruiz-Cortes T; Jove M; Naudí A; Martinez-Redondo P; Dierssen M; Ferrer I; Villarroya F; Pamplona R; Vaquero A; Portero-Otin M; Pujol A. |
Article d'investigació |
| A plasma metabolomic signature discloses human breast cancer. |
2017 |
Jové M; Collado R; Quiles JL; Ramírez-Tortosa MC; Sol J; Ruiz-Sanjuan M; Fernandez M; De la Torre-Cabrera C; Ramirez-Tortosa C; Granados-Principal S; Sanchez-Rovira P; Pamplona R. |
Article d'investigació |
| Adipocyte lipopolysaccharide binding protein (LBP) is linked to a specific lipidomic signature. |
2017 |
Moreno-Navarrete JM; Jove M; Padro T; Boada J; Ortega F; Ricart W; Pamplona R; Badimon L; Portero-Otin M; Fernandez-Real JM. |
Article d'investigació |
| Region-specific vulnerability to lipid peroxidation and evidence of neuronal mechanisms for polyunsaturated fatty acid biosynthesis in the healthy adult human central nervous system |
2017 |
Naudí A, Cabré R, Dominguez-Gonzalez M, Ayala V, Jové M, Mota-Martorell N, Piñol-Ripoll G, Gil-Villar MP, Rué M, Portero-Otín M, Ferrer I, Pamplona R. |
Article d'investigació |
| Targeted metabolomics and medication classification data from participants in the ADNI1 cohort. |
2017 |
St John-Williams L; Blach C; Toledo JB; Rotroff DM; Kim S; Klavins K; Baillie R; Han X; Mahmoudiandehkordi S; Jack J; Massaro TJ; Lucas JE; Louie G; Motsinger-Reif AA; Risacher SL; Alzheimer's Disease |
Article d'investigació |
| Sixty years-old is the breakpoint of the human frontal cortex aging. |
2017 |
Cabré R; Naudí A; Dominguez-Gonzalez M; Ayala V; Jové M; Mota-Martorell N; Piñol-Ripoll G;Gil-Villar MP; Rué M; Portero-Otín M; Ferrer I; Pamplona R |
Article d'investigació |
| A stress-resistant lipidomic signature confers extreme longevity to humans. |
2017 |
Jové M; Naudí A; Gambini J; Borras C; Cabré R; Portero-Otin M; Viña J; Pamplona R |
Article d'investigació |
| Redox proteomic profiling of neuroketal-adducted proteins in human brain: regional vulnerability at middle age increases in the elderly. |
2016 |
Dominguez M; De Oliveira E; Odena MA; Portero M; Pamplona R; Ferrer I. |
Article d'investigació |
| Oral intake of genetically engineered high-carotenoid corn ameliorates hepatomegaly and hepatic steatosis in PTEN haploinsufficient mice. |
2016 |
Eritja N; Arjo G; Santacana M; Gatius S; Arcal L; Serrano JC; Pamplona R; Dolcet X; Piñol C; Christou P; Matias-Guiu X; Portero-Otin M. |
Article d'investigació |
| Metabolomics uncovers the role of adipose tissue PDXK in adipogenesis and systemic insulin sensitivity |
2016 |
Moreno-Navarrete JM, Jove M, Ortega F, Xifra G, Ricart W, Obis E, Pamplona R, Portero Otin M, Fernández-Real JM. |
Article d'investigació |
| Early and gender-specific differences in spinal cord mitochondrial function and oxidative stress markers in a mouse model of ALS |
2016 |
Cacabelos D; Ramírez-Núñez O; Granado-Serrano AB; Torres P; Ayala V; Moiseeva V; Povedano M; Ferrer I; Pamplona R; Portero-Otin M; Boada J. |
Article d'investigació |
| Interplay between TDP-43 and docosahexaenoic acid-related processes in amyotrophic lateral sclerosis |
2016 |
Cacabelos D; Ayala V; Granado-Serrano AB; Jové M; Torres P; Boada J; Cabré R; Ramírez-Núñez O; Gonzalo H; Soler-Cantero A; Serrano JC; Bellmunt MJ, Romero MP; Motilva MJ; Nonaka T; Hasegawa M; Ferrer |
Article d'investigació |
| Rapamycin reverses age-related increases in mitochondrial ROS production at complex I, oxidative stress, accumulation of mtDNA fragments inside nuclear DNA, and lipofuscin level, and increases autopha |
2016 |
Martínez-Cisuelo V, Gómez J, García-Junceda I, Naudí A, Cabré R, Mota-Martorell N, López-Torres M, González-Sánchez M, Pamplona R, Barja G. |
Article d'investigació |
| Specific metabolomics adaptations define a differential regional vulnerability in the adult human cerebral cortex |
2016 |
Cabré R; Jové M; Naudí A; Ayala V; Piñol-Ripoll G; Gil-Villar MP; Dominguez-Gonzalez M; Obis E; Berdun R; Mota-Martorell N; Portero-Otin M; Ferrer I; Pamplona R. |
Article d'investigació |
| Metabolomics Predicts Neuroimaging Characteristics of Transient Ischemic Attack Patients |
2016 |
Purroy F; Cambray S; Mauri-Capdevila G; Jove M; Sanahuja J; Farre J; Benabdelhak I; Molina-Seguin J; Colas-Campas L; Begue R; Gil MI; Pamplona R; Portero-Otin M. |
Article d'investigació |
| Metabotyping human endometrioid endometrial adenocarcinoma reveals an implication of endocannabinoid metabolism |
2016 |
Jove M; Gatius S; Yeramian A; Portero-Otin M; Eritja N; Santacana M; Ruiz M; Pamplona R; Matias-Guiu X. |
Article d'investigació |
| Human Aging Is a Metabolome-related Matter of Gender |
2016 |
Jové M, Maté I, Naudí A, Mota-Martorell N, Portero-Otín M, De la Fuente M, Pamplona R. |
Article d'investigació |
| Deregulation of purine metabolism in Alzheimer's disease |
2015 |
Ansoleaga B, Jove M, Schluter A, Garcia-Esparcia P, Moreno J, Pujol A, Pamplona R, Portero-Otin M, Ferrer I. |
Article d'investigació |
| Altered glycolipid and glycerophospholipid signaling drive inflammatory cascades in adrenomyeloneuropathy |
2015 |
Ruiz M, Jové M, Schlüter A, Casasnovas C, Villarroya F, Guilera C, Ortega FJ, Naudí A, Pamplona R, Gimeno-Martinez R, Fourcade S, Portero-Otín M, Pujol A. |
Article d'investigació |
| Neuroinflammatory Gene Regulation, Mitochondrial Function, Oxidative Stress, and Brain Lipid Modifications With Disease Progression in Tau P301S Transgenic Mice as a Model of Frontotemporal Lobar Dege |
2015 |
López-González I, Aso E, Carmona M, Armand-Ugon M, Blanco R, Naudí A, Cabré R, Portero-Otin M, Pamplona R, Ferrer I. |
Article d'investigació |
| Lipidomics of Human Brain Aging and Alzheimer's Disease Pathology |
2015 |
Naudí A, Cabré R, Jové M, Ayala V, Gonzalo H, Portero-Otín M, Ferrer I, Pamplona R. |
Review |
| Nutridynamics: mechanism(s) of action of bioactive compounds and their effects |
2015 |
Serrano JC, Jove M, Gonzalo H, Pamplona R, Portero-Otin M. |
Article d'investigació |
| Muscle mitohormesis promotes cellular survival via serine/glycine pathway flux |
2015 |
Ost M, Keipert S, Van Schothorst EM, Donner V, Van der Stelt I, Kipp AP, Petzke KJ, Jove M, Pamplona R, Portero-Otin M, Keijer J, Klaus S. |
Article d'investigació |
| Activation of sirtuin 1 as therapy for the peroxisomal disease adrenoleukodystrophy |
2015 |
Morató L, Ruiz M, Boada J, Calingasan NY, Galino J, Guilera C, Jové M, Naudí A, Ferrer I, Pamplona R, Serrano M, Portero-Otín M, Beal MF, Fourcade S, Pujol A. |
Article d'investigació |
| Cysteine dietary supplementation reverses the decrease in mitochondrial ROS production at complex I induced by methionine restriction |
2015 |
Gomez A, Gomez J, Lopez Torres M, Naudí A, Mota-Martorell N, Pamplona R, Barja G. |
Article d'investigació |
| Target of rapamycin activation predicts lifespan in fruit flies |
2015 |
Scialo F, Sriram A, Naudí A, Ayala V, Jové M, Pamplona R, Sanz A. |
Article d'investigació |
| Obesity changes the human gut mycobiome |
2015 |
Rodriguez MM, Chaves FJ, Perez D, Esteve E, Marin-Garcia P, Xifra G, Vendrell J, Jové M, Pamplona R, Ricart W, Portero-Otin M, Chacón MR, Fernández-Real JM. |
Article d'investigació |
| Long lifespans have evolved with long and monounsaturated fatty acids in birds |
2015 |
Galvan I, Naudi A, Erritzoe J, Moller AP, Barja G, Pamplona R. |
Article d'investigació |
| Voltage-gated calcium channel blockers deregulate macroautophagy in cardiomyocytes |
2015 |
Pushparaj C, Das A, Purroy R, Nager M, Herreros J, Pamplona R, Cantí C. |
Article d'investigació |
| Neuroinflammatory signals in Alzheimer's disease and APP/PS1 transgenic mice: correlations with plaques, tangles, and oligomeric species |
2015 |
Lopez-Gonzalez I, Schluter A, Aso E, Garcia-Esparcia P, Ansoleaga B, Llorens F, Carmona M, Moreno J, Fuso A, Portero-Otin M, Pamplona R, Pujol A, Ferrer I. |
Article d'investigació |
| Metabolomics predicts stroke recurrence after transient ischemic attack |
2015 |
Jové M, Mauri-Capdevila G, Suárez I, Cambray S, Sanahuja J, Quílez A, Farré J,Benabdelhak I, Pamplona R, Portero-Otín M, Purroy F. |
Article d'investigació |
| The antioxidant effect of LMN diet, rich in polyphenols and polyunsaturated fatty acids, in Alzheimer’s disease. |
2014 |
Fernandez-Fernandez L; Sole M; Bolea I; Valente T; Serrano JCE; Jove M; Ramirez B; Angles N; Reguant J; Morello JR; Pamplona R; Portero-Otin M; Unzeta M. |
Capítol de llibre docent |
| Estrés oxidativo, inflamación y envejecimiento. |
2014 |
Naudi A; Portero-Otin M; Pamplona R. |
Capítol de llibre docent |
| Caloric restriction reveals a lipidomic and metabolomic signature in liver of male mice. |
2014 |
Jove M; Naudi A; Ramirez O; Portero-Otin M; Selman C; Withers DJ; Pamplona R. |
Article d'investigació |
| Dietary Lipid Unsaturation Influences Survival and Oxidative Modifications of an Amyotrophic Lateral Sclerosis Model in a Gender-Specific Manner |
2014 |
Cacabelos D, Ayala V, Ramirez-Nuñez O, Granado-Serrano AB, Boada J, Serrano JCE, Cabre R, Nadal-Rey G, Bellmunt MJ, Ferrer I, Pamplona R, Portero-Otin M. |
Article d'investigació |
| Independent and additive effects of atenolol and methionine restriction on lowering rat heart mitochondria oxidative stress |
2014 |
Sanchez-Roman I, Gómez A, Naudí A, Jové M, Gomez J, Lopez-Torres M, Pamplona R, Barja G. |
Article d'investigació |
| Plasma lipidomics discloses metabolic syndrome with a specific HDL phenotype |
2014 |
Jové M, Naudí A, Portero-Otin M, Cabré R, Rovira-Llopis S, Bañuls C, Rocha M, Hernández-Mijares A, Victor VM, Pamplona R. |
Article d'investigació |
| Human omental and subcutaneous adipose tissue exhibit specific lipidomic signatures. |
2014 |
Jove M; Moreno-Navarrete JM; Pamplona R; Ricart W; Portero-Otin M; Fernandez-Real JM. |
Article d'investigació |
| Lifelong treatment with atenolol decreases membrane fatty acid unsaturation and oxidative stress in heart and skeletal muscle mitochondria and improves immunity and behaviour, without changing mice lo |
2014 |
Gomez A, Sanchez-Roman I, Gomez J, Cruces J, Mate I, Lopez-Torres M, Naudi A, Portero-Otin M, Pamplona R, De la Fuente M, Barja G. |
Article d'investigació |
| Hydroxytyrosol ameliorates oxidative stress and mitochondrial dysfunction in doxorubicin-induced cardiotoxicity in rats with breast cancer. |
2014 |
Granados-Principal S; El-Azem N; Pamplona R; Ramirez-Tortosa C; Pulido-Moran M; Vera-Ramirez L; Quiles JL; Sanchez-Rovira P; Naudi A; Portero-Otin M; Perez-Lopez P; Ramirez-Tortosa MC. |
Article d'investigació |
| Metabolomics of human aging brain and age-related neurodegenerative diseases. |
2014 |
Jove M; Portero-Otin M; Naudi A; Ferrer I; Pamplona R. |
Review |
| Plasma antioxidant capacity in critical polytraumatized patients?: methods, severity, and anatomic location |
2014 |
Servia, L.; Trujillano, J.; Enrique Serrano, JCE.; Pamplona, R.; Badia, M.; Jove, M.; Justes, M.; Domingo, J.; Portero Otin, M. |
Article d'investigació |
| Membrane lipid unsaturation as physiological adaptation to animal longevity |
2013 |
Naudi A; Jove M; Ayala V; Portero-Otin M; Barja G; Pamplona R |
Article d'investigació |
| Long-life supplementation with atenolol converts the heart and skeletal muscle unsaturation of mitochondrial membranes of mice into those of ten fold longer-lived mammals. Effects on mean and maximum |
2013 |
Gómez A; Naudí A; Pamplona R; Barja G. |
Article d'investigació |
| Non-enzymatic modification of aminophospholipids by carbonyl-amine reactions |
2013 |
Naudi A, Jove M, Ayala V, Cabre R, Portero-Otin M, Pamplona R. |
Review |
| Dietary intake of green tea polyphenols regulates insulin sensitivity with an increase in AMP-activated protein kinase content and changes in mitochondrial respiratory complexes |
2013 |
Serrano JCE, Gonzalo-Benito H, Jové M, Fourcade S, Cassanyé A, Boada J, Delgado MA, Espinel AE, Pamplona R, Portero-Otín M. |
Article d'investigació |
| Atherosclerosis prevention by nutritional factors: a meta-analysis in small animal models. |
2013 |
Jové M; Pamplona R; Prat J; Arola L and Portero-Otín M |
Article d'investigació |
| Exceptionally old mice are highly resistant to lipoxidation-derived molecular damage. |
2013 |
Arranz L; Naudi A; De la Fuente M; Pamplona R. |
Article d'investigació |
| An evolutionary comparative view for longevity-related oxidative stress resistance mechanisms in animal species. |
2013 |
Pamplona R; Barja G. |
Capítol de llibre docent |
| Estrés oxidativo, vulnerabilidad neuronal selectiva, y enfermedades neurodegenerativas asociadas a la edad. |
2013 |
Naudi A; Jove M; Ayala V; Cacabelos D; Ramírez O; Ferrer I; Portero-Otin M; Pamplona R. |
Capítol de llibre docent |
| Impaired mitochondrial oxidative phosphorylation in the peroxisomal disease X-linked adrenoleukodystrophy |
2013 |
López-Erauskin J, Galino J, Ruiz M, Cuezva JM, Fabregat I, Cacabelos D, Boada J, Martínez J, Ferrer I, Pamplona R, Villarroya F, Portero-Otín M, Fourcade S, Pujol A. |
Article d'investigació |
| T-type calcium channel blockers inhibit autophagy and promote apoptosis of malignant melanoma cells |
2013 |
Das A, Pushparaj C, Herreros J, Nager M, Vilella R, Portero M, Pamplona R, Matias-Guiu X, Martí RM, Cantí C. |
Article d'investigació |
| Plasma long-chain free fatty acids predict mammalian longevity |
2013 |
Jove M, Naudi A, Aledo JC, Cabre R, Ayala V, Portero-Otin M, Barja G, Pamplona R. |
Article d'investigació |
| Specific Lipidome Signatures in Central Nervous System from Methionine-Restricted Mice |
2013 |
Jové M, Ayala V, Ramírez-Núñez O, Naudí A, Cabré R, Spickett CM, Portero-Otín M, Pamplona R. |
Article d'investigació |
| Vitamin D receptor BsmI polymorphism modulates soy intake and 25-hydroxyvitamin D supplementation benefits in cardiovascular disease risk factors profile. |
2013 |
Serrano JCE; De Lorenzo D; Cassanye A; Martín-Gari M; Espinel A; Delgado MA; Pamplona R; Portero-Otin M. |
Article d'investigació |
| Estudio de la vulnerabilidad neuronal selectiva en el sistema nervioso central humano. |
2013 |
Naudi A; Jove M; Ayala V; Cabre R; Portero-Otin M; Ferrer I; Pamplona R. |
Article d'investigació |
| Pioglitazone halts axonal degeneration in a mouse model of X-linked adrenoleukodystrophy. |
2013 |
Morató L, Galino J, Ruiz M, Calingasan NY, Starkov AA, Dumont M, Naudi A, Martinez JJ, Aubourg P, Portero-Otín M, Pamplona R, Galea E, Beal MF, Ferrer I, Fourcade S, Pujol A. |
Article d'investigació |
| Skeletal muscle uncoupling-induced longevity in mice is linked to increased substrate metabolism and induction of the endogenous antioxidant defense system. |
2013 |
Keipert S; Ost M; Chadt A; Voigt A; Ayala V; Portero-Otin M; Pamplona R; Al-Hasani H; Klaus S. |
Article d'investigació |
| Lipidomic and metabolomic analyses reveal potential plasma biomarkers of early atheromatous plaque formation in hamsters |
2013 |
Jove M, Ayala V, Ramirez-Nuñez O, Serrano JCE, Cassanye A, Arola L, Caimari A, del Bas JM, Crescenti A, Pamplona R, Portero-Otin M. |
Article d'investigació |
| Tetratdecylthioacetic acid attenuates inflammation and has antioxidative potential during experimental colitis in rats. |
2013 |
Bjorndal B; Grimstad TB; Cacabelos D; Nylund K; Aasprong OG; Omdal R; Portero-Otin M; Pamplona R; Lied GA; Hausken T; Berge RK. |
Article d'investigació |
| A salmon peptide diet alleviates experimental colitis as compared with fish oil |
2013 |
Grimstad T, Bjørndal B, Cacabelos D, Aasprong O; Omdal R, Svardal A, Bohov P, Pamplona R, Portero-Otin M, Berge R, Hausken T. |
Article d'investigació |
| Formation of S-(Carboxymethyl)-cysteine in rat liver mitochondrial proteins. Effects of caloric and methionine restriction. |
2013 |
Naudí A, Jové M, Cacabelos D, Ayala V, Cabré R, Caro P; Gómez J, Portero-Otín M, Barja G, Pamplona R |
Article d'investigació |
| Plant-Derived Phenolics Inhibit the Accrual of Structurally Characterised Protein and Lipid Oxidative Modifications. |
2012 |
Soler-Cantero A; Jové M; Cacabelos D.; Boada J.; Naudí A; Romero M.P.; Cassanyé A; Serrano J; Arola Ll; Valls J; Bellmunt MJ; Prat J; Pamplona R; Portero-Otín M; Motilva MJ |
Article d'investigació |
| Amyloid generation and dysfunctional immunoproteasome activation with disease progression in animal model of familial Alzheimer's disease |
2012 |
Aso E; Lomoio S; López-González I; Joda L; Carmona M; Fernández-Yagüe N; Moreno J; Juvés S; Pujol A; Pamplona R; Portero-Otin M; Martín V; Díaz M; Ferrer I. |
Article d'investigació |
| Region specific vulnerability to lipid peroxidation in the human central nervous system. |
2012 |
Naudi A; Jove M; Ayala V; Ramirez O; Cabre R; Prat J; Portero-Otin M; Ferrer I; Pamplona R. |
Capítol de llibre docent |
| Cellular dysfunction in diabetes as maladaptive response to mitochondrial oxidative stress |
2012 |
Naudí A, Jové M, Ayala V, Cassanye A, Serrano J, Gonzalo H, Boada J, Prat J,Portero-Otín M,Pamplona R |
Review |
| Dietary supplementation of krill oil attenuates inflammation and oxidative stress in experimental ulcerative colitis in rats. |
2012 |
Grimstad T; Bjørndal B; Cacabelos D; Gunnar Aasprong O; Janssen EAM; Omdal R; Svardal A; Hausken T; Bohov P; Portero-Otin M; Pamplona R; Berge RK. |
Article d'investigació |
| DJ-1β regulates oxidative stress, insulin-like signaling and development in Drosophila melanogaster. |
2012 |
Stefanatos R; Sriram A; Kiviranta E; Mohan A; Ayala V; Jacobs HT; Pamplona R; Sanz A. |
Article d'investigació |
| Lipidome analysis in multiple sclerosis reveals protein lipoxidative damage as a potential pathogenic mechanism. |
2012 |
Gonzalo H; Brieva L; Tatzber F; Jové M; Cacabelos D; Cassanyé A; Lanau-Angulo L; Boada J; Serrano JC; González C; Hernández L; Peralta S; Pamplona R; Portero-Otin M. |
Article d'investigació |
| Oxidative stress underlying axonal degeneration in adrenoleukodystrophy: A paradigm for multifactorial neurodegenerative diseases?. |
2012 |
Galea E; Launay N; Portero-Otin M; Ruiz M; Pamplona R; Aubourg P; Ferrer I; Pujol A. |
Review |
| Effects of aging and methionine restriction applied at old age on ROS generation and oxidative damage in rat liver mitochondria. |
2012 |
Sanchez-Roman I; Gómez A; Sanchez C; Suarez H; Naudi A; Jove M; Lopez-Torres M; Pamplona R; Barja G. |
Article d'investigació |
| Functional expression of voltage-gated calcium channels in human melanoma |
2012 |
Das A, Pushparaj C, Bahí N, Sorolla A, Herreros J, Pamplona R, Vilella R, Matias-Guiu X, Martí RM, Cantí C. |
Article d'investigació |
| Fish oil and 3-thia fatty acid have additive effects on lipid metabolism but antagonistic effects on oxidative damage when fed to rats for 50 weeks. |
2012 |
Vigerust NAF; Cacabelos D; Burri L; Berge K; Wergedahl H; Christensen B; Portero-Otin M; Viste A; Pamplona R; Berge RK; Bjørndal B. |
Article d'investigació |
| Membrane unsaturation, selective neuronal vulnerability, and age-related neurodegenerative diseases. |
2011 |
Naudi A; Jove M; Cacabelos D; Ramirez O; Ayala V; Ilieva EV; Kichev A; Ferrer I; Portero-Otin M; Pamplona R. |
Capítol de llibre d'investigació |
| Regultation of membrane unsaturation as antioxidant adaptative mechanism in long-lived animal species |
2011 |
Naudí A, Jové M, Ayala V, Portero-Otín M, Barja G, Pamplona R. |
Article d'investigació |
| Forty percent methionine restriction lowers DNA methylation, complex I ROS generation, and oxidative damage to mtDNA and mitochondrial proteins in rat heart. |
2011 |
Sanchez-Roman I; Gomez A; Gomez J; Suarez H; Sanchez C; Naudi A; Ayala V; Portero-Otin M; Lopez-Torres M; Pamplona R; Barja G. |
Article d'investigació |
| An evolutionary comparative scan for longevity-related oxidative stress resistance mechanisms in homeotherms. |
2011 |
Pamplona R; Barja G. |
Article d'investigació |
| Molecular and structural antioxidant defences against oxidative stress in animals. |
2011 |
Pamplona R; Costantini D. |
Review |
| Multicompartmental LC-Q-TOF-Based Metabonomics as an exploratory tool to identify novel pathways affected by polyphenol-rich diets in mice. |
2011 |
Jove, M; Serrano, JCE; Ortega, N; Ayala, V; Angles, N; Reguant, J ; Morello, JR; Romero, MP ; Motilva, MJ; Prat, J ; Pamplona, R ; Portero-Otin, M |
Article d'investigació |
| Prefrontal cortex, caloric restriction and stress during aging: studies on dopamine and acetylcholine release, BDNF and working memory. |
2011 |
Del Arco A, Segovia G, De Blas M, Garrido P, Acuña-Castroviejo D, Pamplona R, Mora F. |
Article d'investigació |
| Antioxidants halt axonal degeneration in a mouse model of X-adenoleukodystrophy |
2011 |
López-Erauskin J, Fourcade S, Galino J, Ruiz M, Schlüter A, Naudi A, Jove M, Portero-Otin M, Pamplona R, Ferrer I, Pujol A. |
Article d'investigació |
| Oxidative damage compromises energy metabolism in the axonal degeneration mouse model of X-adrenoleukodystrophy |
2011 |
Galino J, Ruiz M, Fourcade S, Schlüter A, López-Erauskin J, Guilera C, Jove M, Naudi A, García-Arumí E, Andreu AL, Starkov AA, Pamplona R, Ferrer I, Portero-Otin M, Pujol A. |
Article d'investigació |
| Mitochondrial dysfunction and oxidative and endoplasmatic reticulum stress in argyrophilic grain disease |
2011 |
Ilieva EV, Kichev A, Naudí A, Ferrer I, Pamplona R, Portero-Otín M. |
Article d'investigació |
| Mitochondria and aging |
2011 |
Sanz A; Pamplona R; Leeuwenburgh C. |
Review |
| Advanced Lipoxidation End-Products. |
2011 |
Pamplona R. |
Review |
| Mitochondrial DNA damage and animal longevity: Insights from comparative studies |
2011 |
Pamplona R. |
Article d'investigació |
| Cell stress induces TDP-43 pathological changes associated with ERK1/2 dysfunction: implications in ALS |
2011 |
Ayala V, Granado-Serrano AB, Cacabelos D, Naudí A, Ilieva EV, Boada J, Caraballo-Miralles V, Lladó J, Ferrer I, Pamplona R, Portero-Otin M. |
Article d'investigació |
| Nutrigenómica y nutrigenética. Hacia la dieta personalizada. |
2011 |
De Lorenzo D; Serrano J; Portero-Otin M; Pamplona R. |
Editor llibre docent |
| Resistencia a la insulina: ¿factor de riesgo o adaptación fisiológica?. |
2011 |
Pamplona R; Serrano J; Boada J; Ayala V; Bellmunt MJ; Espinel A; Delgado MA; Portero-Otin M. |
Capítol de llibre docent |
| Age-related changes in brain mitochondrial DNA deletion and oxidative stress are differentially modulated by dietary fat type and coenzyme Q10 |
2011 |
Ochoa JJ, Pamplona R, Ramirez-Tortosa MC, Granados-Principal S, Perez-Lopez P, Naudí A, Portero-Otin M, López-Frías M, Battino M, Quiles JL. |
Article d'investigació |
| Stanozolol treatment decreases the mitochondrial ROS generation and oxidative stress induced by acute exercice in rat skeletal muscle |
2011 |
Saborido A, Naudí A, Portero-Otín M, Pamplona R, Megías A. |
Article d'investigació |
| Mitochondrial ATP-synthase in the entorhinal cortex is target of oxidative stress at stages I/II of Alzheimer's disease |
2010 |
Terni B, Boada J, Portero-Otin M, Pamplona R, Ferrer I |
Article d'investigació |
| Coenzyme Q addition to and n6PUFA-rich diet partially resembles benefits on age-related mtDNA deletions and oxidative stress of a MUFA-rich diet in rat heart |
2010 |
Quiles JL, Pamplona R, Ramirez-Tortosa MC, Naudi A, Portero-Otin M, Araujo-Nepomuceno E, Lopez-Frias M, Battino M, Mataix J, Ochoa JJ |
Article d'investigació |
| Longevity, Mitochondria and Oxygen free radicals |
2010 |
Pamplona R, Barja G. |
Editor llibre docent |
| Oxidative stress resistance and longevity. |
2010 |
Pamplona R, Barja G. |
Capítol de llibre docent |
| Estres oxidativo, envejecimiento y longevidad- |
2010 |
Pamplona R. |
Capítol de llibre docent |
| Valproic acid induces antioxidant effects in X-adrenoleukodystrophy. |
2010 |
Fourcade S, RUiz M, Guilera C, Hahnen E, Brichta L, Naudi A, Portero M, Dacremont G, Cartier N, Wanders R, Kemp S, Mandel JL, Wirth B, Pamplona R, Aubourg P, Pujol A. |
Article d'investigació |
| Depletion of oxidative and endoplasmic reticulum stress regulators in Pick disease. |
2010 |
Ilieva EV, Naudi A, Kichev A, Ferrer I, Pamplona R, Portero-Otin M. |
Article d'investigació |
| Modification of brain lipids but not phenotype in alpha-synucleinopathy transgenic mice by long-term dietary n-3 fatty acids |
2010 |
Muntane G, Janue A, Fernandez N, Odena MA, Oliveira E, Boluda S, Portero-Otin M, Naudi A, Boada J, Pamplona R, Ferrer I. |
Article d'investigació |
| Effects of Increased Iron Intake During the Neonatal Period on the Brain of Adult A beta PP/PS1 Transgenic Mice |
2010 |
Fernandez L, Carmona M, Portero-Otin M, Naudi A, Pamplona R, Schroder N, Ferrer I. |
Article d'investigació |
| Protein targets of oxidative damage in human neurodegenerative diseases with abnormal protein aggregates. |
2010 |
Martinez A, Portero-Otin M, Pamplona R, Ferrer I. |
Article d'investigació |
| Biomarkers of ageing in Drosophila |
2010 |
Jacobson J, Lambert A, Portero-Otin M, Pamplona R, Magwere T, Miwa S, Driege Y, Brand MD, Partridge L. |
Article d'investigació |
| Mitochondrial DNA mutations induce mitochondrial dysfunction, apoptosis and sarcopenia in skeletal muscle of mitochondrial DNA mutator mice. |
2010 |
Hiona A, Sanz A, Kujoth GC, Pamplona R, Seo AY, Hofer T, Someya S, Miyagawa T, Nakayama C, Samhan-Arias AK, Servais S, Barger JL, Portero-Otin M, Tanokura M, Prolla TA, Leeuwenburgh C. |
Article d'investigació |
| The beta-blocker atenolol lowers the longevity-related degree of fatty acid unsaturation, decreases protein oxidative damage and increases ERK signaling in heart of C57BL/6 mice. |
2010 |
Sanchez-Roman I, Gomez J, Naudi A, Ayala V, Portero-Otin M, Lopez-Torres M, Pamplona R, Barja G. |
Article d'investigació |
| Dietary restriction and aging: a matter of calories? |
2010 |
Pamplona R. |
Review |
| Pathological aspects of lipid peroxidation |
2010 |
Negre-Salvayre A; Auge N; Ayala V; Basaga H; Boada J; Brenke R; Chapple S; Cohen G; Feher J; Grune T; Lengyel G; Mann GE; Pamplona R; Poli G; Portero-Otin M; Riahi Y; Salvayre R; Sasson S; Serrano J; |
Article d'investigació |
| Glycation of mitochondrial proteins, oxidative stress and aging |
2010 |
Naudí A, Jové M, Ayala V, Portero-Otín M, Pamplona R |
Article d'investigació |
| Double-edged sword behaviour of gallic acid and its interaction with peroxidases in human microvascular endothelial cell culture (HMEC-1). Antioxidant and pro-oxidant effects |
2010 |
Serrano J; Cipak A; Boada J; Gonzalo H; Cacabelos D; Cassanye A; Pamplona R; Zarkovic N; Portero-Otin M |
Article d'investigació |
| Protein oxidative damage in diabetes |
2010 |
Pamplona R; Ayala V; Boada J; Serrano J; Portero-Otin M. |
Capítol de llibre docent |
| When cholesterol is not cholesterol: a note on the enzymatic determination of its concentration in model systems containing vegetable extracts |
2010 |
Jové, M.; Serrano, J.C.; Bellmunt, M.J.; Cassanyé, A.; Anglès, N.; Reguant, J.; Morellá, J.R.; Pamplona, R.; Portero-Otín, M. |
Article d'investigació |
| Expression of the yeast NADH dehydrogenase Ndi1 in Drosophila confers increased lifespan independently of dietary restriction |
2010 |
Sanz A; Soikkeli M; Portero-Otín M; Wilson A; Kemppainen E; McIlroy G; Ellilä S; Kemppainen KK; Tuomela T; Lakanmaa M; Kiviranta E; Stefanatos R; Dufour E; Hutz B; Naudí A; Jové M; Zeb A; Vartiainen S |
Article d'investigació |
| Endogenous toxins associated with life expectancy and aging |
2010 |
Ayala V, Boada J, Serrano J, Portero-Otin M, Pamplona R |
Capítol de llibre docent |
| Effect of methionine dietary supplementation on mitochondrial oxygen radical generation and oxidative DNA damage in rat liver and heart |
2009 |
Gomez J, Caro P, Sanchez I, Naudi A, Jove M, Portero-Otin M, Lopez-Torres M, Pamplona R, Barja G |
Article d'investigació |
| El mito de las dietas y farmacos milagrosos |
2009 |
Pamplona R |
Capítol de llibre docent |
| Estrés Oxidativo y Lípidos: determinación del índice de peroxidabilidad de los lípidos de membrana y la lesión lipoxidativa a proteínas. |
2009 |
Naudí A,Jové M, Cacabelos D,Ilieva E, Gonzalo H, Serrano J, Ayala V, Boada J, Portero-Otín M, Pamplona R. |
Capítol de llibre docent |
| Biogerontologia Medica |
2009 |
Sastre J, Pamplona R, Ramon J |
Editor llibre docent |
| Restricción calórica, envejecimiento y longevidad |
2009 |
Pamplona R, Barja G |
Capítol de llibre docent |
| Free radicals and mammalian aging |
2009 |
Sanz A, Barja G, Pamplona R, Leeuwenburgh C |
Capítol de llibre docent |
| Oxidación de Macromoléculas, Envejecimiento y Longevidad |
2009 |
Naudí A,Jové M,Ilieva E, Cacabelos D, Gonzalo H, Serrano J,Boada J, Ayala V, Portero-Otín M, Pamplona R. |
Capítol de llibre docent |
| Forty percent methionine restriction decreases mitochondrial oxygen radical production and leak at complex I during forward electron flow and lowers oxidative damage to proteins and mitochondrial DNA |
2009 |
Caro P, Gomez J, Sanchez I, Naudi A, Ayala V, Lopez-Torres M, Pamplona R, Barja G. |
Article d'investigació |
| Dietary antioxidants interfere with Amplex Red-coupled-fluorescence assays |
2009 |
Serrano J, Jové M, Boada J, Bellmunt MJ, Pamplona R, Portero-Otín M |
Article d'investigació |
| Cell death and learning impairment in mice caused by in vitro modified pro-NGF can be related to its increased oxidative modifications in Alzheimer's disease. |
2009 |
Kichev A, Ilieva EV, Piñol-Ripoll G, Podlesniy P, Ferrer I, Portero-Otin M, Pamplona R, Espinet C |
Article d'investigació |
| Human Life and Aging |
2009 |
Pamplona R |
Review |
| How to write and evaluate a scientific article for Revista Española de Geriatria y Gerontologia |
2009 |
Formiga F, Baztan JJ, Montorio I, Pamplona R, Rodriguez-Molinero A |
Article d'investigació |
| Caloric restriction and aging in humans |
2009 |
Pamplona R |
Review |
| Effect of 40% restriction of dietary amino acids -except methionine- on mitochondria oxidative stress and biogenesis, AIF and SIRT1 in rat liver. |
2009 |
Caro P, Gomez J, Sanchez I, Garcia R, López-Torres M, Naudí A, Portero M.,Pamplona R, Barja G. |
Article d'investigació |
| Hyperglycemia and glycation in diabetic complications |
2009 |
Negre-Salvayre A, Salvayre R, Auge N, Pamplona R, Portero-Otin M |
Review |
| Bases biológicas del proceso de envejecimiento y la longevidad |
2009 |
Naudí A,Caro P, Barja G, Pamplona R |
Capítol de llibre docent |
| Type-dependent oxidative damage in frontotemporal lobar degeneration; cortical astrocytes are targets of oxidative damage |
2008 |
Martínez A, Carmona M, Portero-Otin M, Naudí A, Pamplona R, Ferrer I. |
Article d'investigació |
| Innovación educativa en la universidad: la enseñanza de la Fisiología en el grado de Medicina. |
2008 |
Gallego-Fernández R(ed.), Palés JL, Escanero JF, Sánchez-Bar E y colaboradores. |
Llibre docent |
| Resistencia a la insulina: factores desencadenantes |
2008 |
Pamplona R, Boada J, Jove M, Gonzalo H, Bellmunt MJ and Portero-Otín M |
Capítol de llibre docent |
| Membrane phospholipids, lipoxidative stress and molecular integrity:a causal role in aging and longevity |
2008 |
Pamplona R |
Review |
| Inhibition of the renin-angiotensin system decreases renal protein oxidative damage in diabetic rats |
2008 |
Portero-Otin M, Pamplona R, Boada J, Jove M, Gonzalo H, Buleon M, Linz W, Schafer S, Tack I, Girolami JP |
Article d'investigació |
| Early oxidative damage underlying neurodegeneration in x-adrenoleukodystrophy |
2008 |
Fourcade S, Lopez-Erauskin J, Galino J, Duval C, Naudi A, Jove M, Villarroya F, Ferrer I, Pamplona R, Portero-Otin M, Pujol A |
Article d'investigació |
| Effect of every other day feeding on mitochondrial free radical production and oxidative stress in mouse liver |
2008 |
Caro P, Gomez J, Lopez-Torres M, Sanchez I, Naudi A, Portero-Otin M, Pamplona R, Barja G |
Article d'investigació |
| Forty percent and eighty percent methionine restriction decrease mitochondrial ROS generation and oxidative stress in rat liver |
2008 |
Caro P, Gomez J, Lopez-Torres M, Sanchez I, Naudi A, Jove M, Pamplona R, Barja G |
Article d'investigació |
| Maillard reaction versus other nonenzymatic modifications in neurodegenerative processes |
2008 |
Pamplona R, Ilieva E, Ayala V, Bellmunt MJ, Cacabelos D, Dalfo E, Ferrer I, Portero-Otin M |
Article d'investigació |
| Increased oxidation, glycoxidation and lipoxidation of brain proteins in prion disease. |
2008 |
Pamplona R, Naudi A, Gavin R, Pastrana MA, SajnaniG, Ilieva E, del Rio JA, Portero-Otin M, Ferrer I, Requena JR |
Article d'investigació |
| The biological basis of the aging process |
2007 |
Naudi A, Jove M, Cacabelos D, Ilieva E, Boada J, Ayala V, Portero-Otin M, Pamplona R |
Review |
| Estrés oxidativo, envejecimeinto y longevidad |
2007 |
Pamplona R |
Capítol de llibre docent |
| Effect of graded corticosterone treatment on aging-related markers of oxidative stress in rat liver mitochondria |
2007 |
Caro P, Gomez J, Sanz A, Portero-Otin M, Pamplona R, Barja G |
Article d'investigació |
| Dietary protein restriction decreases oxidative protein damage, peroxidizability index, and mitochondrial complex I content in rat liver |
2007 |
Ayala V, Naudí A, Sanz A, Caro P, Portero-Otin M, Barja G, Pamplona R. |
Article d'investigació |
| Life and death: metabolic rate, membrane composition and life span. |
2007 |
Hulbert AJ, Pamplona R, Buffenstein R, Buttemer W |
Review |
| Oxidative and endoplasmic reticulum stress interplay in sporadic amyotrophic lateral sclerosis |
2007 |
Ilieva EV, Ayala V, Jove M, Dalfo E, Cacabelos D, Povedano M, Bellmunt MJ, Ferrer I, Pamplona R, Portero-Otin M. |
Article d'investigació |
| Effect of 8.5% and 25% caloric restriction on mitochondrial free radical production and oxidative stress in rat liver |
2007 |
Gomez J, Caro P, Naudi A, Portero-Otin M, Pamplona R, Barja G |
Article d'investigació |
| Methylglyoxal induces advanced glycation endproduct (AGEs) formation and dysfunction of PDGF receptor-beta. Implications for diabetic atherosclerosis |
2007 |
Cantero AV, Portero-Otin M, Sanson M, Ayala V, Auge N, Elbaz M, Thiers JC, Pamplona R, Salvayre R, Negre-Salvayre A |
Article d'investigació |
| Highly resistant macromolecular components and low rate of generation of endogenous damage: two key traits of longevity |
2007 |
Pamplona R, Barja G |
Review |
| Methionine restriction decreases endogenous oxidative molecular damage and increases mitochondrial biogenesis and uncoupling protein 4 in rat brain |
2007 |
Naudi A, Caro P, Jove M, Gomez J, Boada J, Ayala V, Portero-Otin M, Barja G, Pamplona R |
Article d'investigació |
| Differential effect of experimental and cold-induced hyperthyoridism on factors inducing rat liver oxidative damage. |
2006 |
Venditti P, Pamplona R, Ayala V, De Rosa R, Caldarone G, DiMeo S. |
Article d'investigació |
| Glial fibrillary acidic protein is a major target of glycoxidative and lipoxidative damage in Pick's disease |
2006 |
Muntane G, Dalfo E, Martinez A, Rey MJ, Avila J, Perez M, Portero M, Pamplona R, Ayala V, Ferrer I. |
Article d'investigació |
| Is the mitochondrial free radical theory of aging intact? |
2006 |
Sanz A, Pamplona R, Barja G. |
Article d'investigació |
| Effects of fasting on oxidative stress in rat liver mitochondria |
2006 |
Sorensen M, Sanz A, Gomez J, Pamplona R, Portero-Otin M, Gredilla R, Barja G. |
Article d'investigació |
| Flight activity, mortality rates, and lipoxidative damage in Drosophila. |
2006 |
Magwere T, Pamplona R, Miwa S, Martinez-Diaz P, Portero-Otin M, Brand MD, Partridge L. |
Article d'investigació |
| Lesion oxidativa de proteinas de higado y corazon de rata durante el proceso de envejecimiento. |
2006 |
Ayala V, Vasileva E, Fernandez E, Modol MT, Bellmunt MJ, Prat J, Requena JR, Portero-Otin M, Pamplona R. |
Article d'investigació |
| Mitochondrial oxidative stress, aging and caloric restriction: the protein and methionine connection |
2006 |
Pamplona R,Barja G. |
Article d'investigació |
| Effect of experimental and cold exposure induced hyperthyoridism on H2O2 production and susceptibility to oxidative stress of rat liver mitochondria. |
2006 |
Venditti P, Pamplona R, Portero-Otin M, De Rosa R, DiMeo S. |
Article d'investigació |
| Methionine restriction decreases mitochondrial oxygen radical generation and leak and oxidative damage to mitochondrial DNA and proteins. |
2006 |
Sanz A, Caro P, Ayala V, Portero-Otin M, Pamplona R and Barja G. |
Article d'investigació |
| Is endogenous oxidative protein damage envolved in the aging process? |
2006 |
Portero-Otin M, Pamplona R. |
Capítol de llibre docent |
| Evidence of oxidative stress in the neocortex in incidental Lewy body disease. |
2005 |
Dalfo E, Portero-Otin M, Ayala MV, Martinez A, Pamplona R, Ferrer I. |
Article d'investigació |
| Regulation of longevity by mitochondria: Role of free radical production and membrane unsaturation.A comparative approach. |
2005 |
Barja G, Portero-Otin M, Pamplona R. |
Capítol de llibre docent |
| Effect of insulin and growth hormone on rat heart and liver oxidative stress in control and caloric restricted animals |
2005 |
Sanz A, Gredilla R, Pamplona R, Portero-Otin M, Vara E, Tresguerres J, Barja G |
Article d'investigació |
| Proteins in human brain cortex are modified by oxidation, glycoxidation and lipoxidation: effects of Alzheimer's disease and identification of lipoxidation targets. |
2005 |
Pamplona R, Dalfo E, Ayala MV, Bellmunt MJ, Prat J, Ferrer I, Portero-Otin M. |
Article d'investigació |
| Protein and lipid oxidative damage and complex I content are lower in the brain of budgerigar and canaries than in mice. Relation to aging rate. |
2005 |
Pamplona R, Portero-Otin M, Sanz A, Ayala V, Vasileva E, Barja G. |
Article d'investigació |
| Protein methionine content and MDA-lysine adducts are inversely related to maximum life span in the heart of mammals |
2005 |
Ruiz MC, Ayala V, Portero-Otin M, Requena JR, Barja G, Pamplona R. |
Article d'investigació |
| Cold-induced hyperthyroidism produces oxidative damage in rat tissues and increases susceptibility to oxidants. |
2004 |
Venditti P, De Rosa R, Portero-Otin M, Pamplona R, DiMeo S. |
Article d'investigació |
| Effect of ageing and caloric restriction on specific markers of protein oxidative damage and membrane peroxidizability in rat liver mitochondria. |
2004 |
Lambert AJ, Portero-Otin M, Pamplona R, Merry BJ. |
Article d'investigació |
| Modification of the longevity-related degree of fatty acid unsaturation modulates oxidative damage to proteins and mitochondrial DNA in liver and brain. |
2004 |
Pamplona R, Portero-Otin M, Sanz A, Requena JR, Barja G. |
Article d'investigació |
| Protein nonenzymatic modifications and proteasome activity in skeletal muscle from the short-lived rat and long-lived pigeon. |
2004 |
Portero-Otin M, Requena JR, Bellmunt MJ, Ayala V, Pamplona R. |
Article d'investigació |
| AGEs in urine: are some sugars-derived products better than others? |
2004 |
Pamplona R, Portero-Otin M. |
Article d'investigació |
| A signalling role for 4-hydroxy-2-nonenal in regulation of mitochondrial uncoupling. |
2003 |
Echtay KS, Esteves T, Pakay JL, Jekabsons MB, Portero-Otin M, Pamplona R, Vidal-Puig AJ, Cawthorne MA, Roebuck SJ, Brand MD. |
Article d'investigació |
| Chemical and immunological characterization of oxidative nonenzymatic protein modifications in dialysis fluids |
2003 |
Ruiz MC, Portero-Otin M, Pamplona R, Requena JR, Prat J, Lafarga MA, Borras M, Bellmunt MJ. |
Article d'investigació |
| Aging rate, free radical production, and constitutive sensitivity to lipid peroxidation: insights from comparative studies. |
2003 |
Pamplona R, Barja G. |
Capítol de llibre docent |
| Protein modification by advanced Maillard adducts can be modulated by dietary polyunsaturated fatty acids. |
2003 |
Portero-Otin M, Bellmunt MJ, Requena JR, Pamplona R. |
Article d'investigació |
| Protein oxidative stress in dialysis patients. |
2002 |
Doñate T, Herreros A, Martinez E, Martinez J, Andres E, Cabezas A, Ortiz A, De Prado A, Pou JM, Pamplona R, Portero-Otin M, Bellmunt MJ. |
Capítol de llibre d'investigació |
| Advanced glycation end product precursors impair epidermal growth factor receptor signaling |
2002 |
Portero-Otin M, Pamplona R, Bellmunt MJ, Ruiz MC, Prat J, Salvayre R, Negre-Salvayre A. |
Article d'investigació |
| Oxidative, glycoxidative and lipoxidative damage to rat heart mitochondrial proteins is lower after four months of caloric restriction than in age-matched control. |
2002 |
Pamplona R, Portero-Otin M, Requena JR, Gredilla R, Barja G. |
Article d'investigació |
| Aging increases Nepsilon-(carboxymethyl)lysine and caloric restriction decreases Nepsilon-(carboxyethyl)lysine and Nepsilon-(malondialdehyde)lysine in rat heart mitochondrial proteins. |
2002 |
Pamplona R, Portero-Otin M, Bellmunt MJ, Gredilla R, Barja G. |
Article d'investigació |
| Membrane fatty acid unsaturation, protection against oxidative stress, and maximum life span - A homeoviscous-longevity adaptation? |
2002 |
Pamplona R, Barja G, Portero-Otin M. |
Review |
| Oxidative damage and phospholipid fatty acyl composition in skeletal muscle mitochondria from mice underexpresing or overexpressing uncoupling protein 3. |
2002 |
Brand MD, Pamplona R, Portero-Otin M, Requena JR, Roebuck SJ, Buckingham JA, Clapham JC, Cadenas S. |
Article d'investigació |
| Effect of the degree of fatty acid unsaturation of rat heart mitochondria on their rates of H2O2 production and lipid and protein oxidative damage. |
2001 |
Herrero A, Portero-Otin M, Bellmunt MJ, Pamplona R, Barja G. |
Article d'investigació |
| Correlation of fatty acid unsaturation of the major liver mitochondrial phospholipid classes in mammals to their maximum life span potential. |
2001 |
Portero-Otin M, Bellmunt MJ, Ruiz MC, Barja G, Pamplona R. |
Article d'investigació |
| Influence of hyper- and hypothyroidism on lipid peroxidation, unsaturation of phospholipids, glutathione system and oxidative damage to nuclear and mitochondrial DNA in mice skeletal muscle. |
2001 |
Gredilla R, Lopez-Torres M, Portero-Otín M, Pamplona R, Barja G. |
Article d'investigació |
| Low fatty acid unsaturation: a mechanism for lowered lipoperoxidative modification of tissue proteins in mammalian species with long life span. |
2000 |
Pamplona R, Portero-Otín M, Riva D, Requena JR, Thorpe SR, López-Torres M, Barja G. |
Article d'investigació |
| Double bond content of phospholipids and lipid peroxidation negatively correlate with maximum longevity in the heart of mammals. |
2000 |
Pamplona R, Portero-Otin M, Ruiz MC, Gredilla R, Herrero A, Barja G. |
Article d'investigació |
| Nonenzymatic modification of aminophospholipids by the Maillard reaction in vivo. |
2000 |
Portero-Otin M, Bellmunt MJ, Ruiz MC, Pamplona R. |
Capítol de llibre docent |
| Diabetes induces an impairment in the proteolytic activity against oxidized proteins and a heterogeneous effect in nonenzymatic protein modifications in the cytosol of rat liver and kidney. |
1999 |
Portero Otín, M.; Pamplona R.; Ruiz MC.; Cabiscol E.; Prat J.; Bellmunt MJ. |
Article d'investigació |
| A low degree of fatty acid unsaturation leads to lower lipid peroxidation and lipoxidation derived protein modification in heart mitochondria of the longevous pigeon than in the short-lived rat. |
1999 |
Pamplona R, Portero-Otin M, Requena JR, Thorpe SR, Herrero A, Barja G. |
Article d'investigació |
| Heart fatty acid unsaturation and lipid peroxidation, and aging rate, are lower in the canary and the parakeet than in the mouse |
1999 |
Pamplona R, Portero M, Riba D, Ledo F, Gredilla R, Herrero A, Barja G. |
Article d'investigació |
| Effects of thyroid status on lipid composition and peroxidation in the mice liver |
1999 |
Guerrero A, Pamplona R, Portero M, Barja G, López-Torres M. |
Article d'investigació |
| Tyroid status modulates glycoxidative and lipoxidative modification of tissue proteins. |
1999 |
Pamplona R, Portero M, Ruiz MC, Bellmunt MJ, Requena JR, Thorpe SR, Baynes JW, Romero M, López-Torres M, Barja G. |
Article d'investigació |
| Azúcar, diabetes y envejecimiento. |
1998 |
Pamplona R |
Editor llibre docent |
| Carboxymethylated phosphatidylethanolamine in mithocondrial membranes of mammals: evidence for intracellular lipid glycoxidation |
1998 |
Pamplona R, Requena JR, Portero-Otin M, Prat J, Thorpe SR, Bellmunt MJ. |
Article d'investigació |
| Mitochondrial membrane peroxidizability index is inversely related to maximum life span in mammals |
1998 |
Pamplona R, Portero-Otin M, Riba D, Ruiz MC, Prat J, Bellmunt MJ, Barja G. |
Article d'investigació |
| Urinary pyrraline as a biochemical marker of non-oxidative Maillard reactions in vivo |
1997 |
Portero,M; Pamplona,R; Bellmunt,MJ; Bergua,M; Nagaraj,RH; Prat,J |
Article d'investigació |
| La membrana mitocondrial y la longevidad de los mamíferos. |
1997 |
Pamplona R. |
Review |
| Glycaemic control and in vivo non-oxidative Maillard reaction: urinary excretion of pyrraline in diabetes patients |
1997 |
Portero,M; Pamplona,R; Bellmunt,MJ; Bergua,M; Prat,J |
Article d'investigació |
| Low fatty acid unsaturation protects against lipid peroxidation in liver mitochondria from longevous species: the pigeon and human case. |
1996 |
Pamplona R, Prat J, Lopez-Torres M, Perez-Campo R, Rojas C, Cadenas S, Barja G. |
Article d'investigació |
| Effect of dietary vitamin E on fatty acid profiles and non-enzymatic lipid peroxidation in the guinea pig liver. |
1996 |
Barja G, Cadenas S, Rojas C, Perez-Campo R, Lopez-Torres M, Prat J, Pamplona R. |
Article d'investigació |
| Composición en ácidos grasos de los pescados en conserva más comunes en la dieta española. Dieta y lípidos marinos (y II). |
1996 |
Portero M, Aragon M, Vilardell F, Pamplona R, Bellmunt MJ, Prat J. |
Article d'investigació |
| Age-related fluorescence in rat lung collagen. |
1995 |
Bellmunt MJ, Portero M, Pamplona R, Muntaner M, Prat J. |
Article d'investigació |
| Evidence for Maillard reaction in rat lung collagen and its relationship with solubility and age. |
1995 |
Bellmunt MJ, Portero M, Pamplona R, Cosso L, Odetti P, Prat J. |
Article d'investigació |
| Composición en ácidos grasos de los pescados más comunes de la dieta española. Dieta y lípidos marinos. |
1995 |
Vilardell F, Portero M, Aragon M, Bellmunt MJ, Pamplona R, Prat J. |
Article d'investigació |
| Chromatographic evidence for Amadori product formation in rat liver aminophospholipids. |
1995 |
Pamplona R, Bellmunt MJ, Portero M, Riba D, Prat J. |
Article d'investigació |
| Glicación no enzimática y diabetes. |
1995 |
Pamplona R |
Llibre d'investigació |
| Dietary vitamin C decreases endogenous protein oxidative damage, malondialdehyde, and lipid peroxidation and maintains fatty acid unsaturation in the guinea pig liver. |
1994 |
Barja G, Lpoez M, Perez-Campo R, Rojas C, Cadenas S, Prat J, Pamplona R. |
Article d'investigació |
| Factores de riesgo cardiovascular y alimentación en el Pallars Sobirà (Lleida). |
1994 |
Bergua M, Moron P, Muñoz M, Marion G, Pamplona R, Prat J, Lloveras G. |
Article d'investigació |
| Glycation, antioxidants and vascular disease. |
1994 |
Pamplona R, Portero M, Costa S, Bellmunt MJ, Prat J. |
Capítol de llibre d'investigació |
| Relationship between lipid peroxidation, fatty acid composition and ascorbic acid in the liver during carbohydrate and caloric restriction in mice. |
1993 |
Rojas C, Cadenas S, Perez-Campo R, Lopez-Torres M, Pamplona R, Prat J, Barja G. |
Article d'investigació |
| Mechanisms of glycation in atherogenesis. |
1993 |
Pamplona R, Bellmunt MJ, Portero M, Prat J. |
Review |
| Composició en àcids greixosos dels peixos més comuns de la dieta. |
1991 |
Vilardell F, Portero M, Aragon M, Bellmunt MJ, Pamplona R, Prat J. |
Article d'investigació |
| Glicación de apolipoproteínas. Implicaciones sobre las complicaciones vasculares de la diabetes |
1991 |
Prat J, Pamplona R, Sorribas A, Navarro X. |
Review |
| Hemoglobina glicada y lípidos plasmáticos en una población no diabética. |
1989 |
Prat J, Sorribas A, Pamplona R, Viñallonga M. |
Article d'investigació |
| Correlation of plasma lipid fractions with colorimetrically-determined glycated hemoglobin in a non diabetic population |
1989 |
Prat J, Pamplona R, Sorribas A, Martin S, Viñallonga M, Segura R. |
Article d'investigació |
