Bachelor's degree Biomedical Sciences


Academic profile: Doctorate


Teaching Course Subject
Master's Degree in Biomedical Research 1 MODEL ORGANISMS IN BIOMEDICINE
Grau en Medicina 1 HUMAN GENETICS
Degree in Biomedical Sciences 1 MOLECULAR BIOLOGY
Degree in Biomedical Sciences 3 CANCER I
Degree in Biomedical Sciences 4 INSTRUMENTAL TECHNIQUES II
Degree in Biomedical Sciences 4 STRESS IN BIOLOGICAL SYSTEMS


Research profile: Cicle Cel·lular Eucariota
Research projects Start date End date Main researchers
Respuesta de la levadura Saccharomyces Cerevisiae a estres oxidativo. Función de las Glutaredoxinas 28/12/2001 27/12/2004 ENRIQUE HERRERO PERPIÑAN
Pueden los anillos de cohesina capturar cromátidas no hermanas? Propuesta de un nuevo modelo para el ensamblaje de la cohesión cromosómica 01/09/2014 30/04/2017 JORDI TORRES ROSELL
Inestabilidad Genómica (INESGEN) 01/10/2007 09/12/2013 MARTI ALDEA MALO
Función del complejo Smc5/6 durante la replicación de los cromosomas en células eucariotas. 01/01/2006 31/12/2008 JORDI TORRES ROSELL
Mecanismos moleculares de disyunción de cromosomas en mitosis 01/01/2016 31/12/2018 MARIA NEUS COLOMINA GABARRELLA, JORDI TORRES ROSELL
Mecanismos moleculares implicados en coordinar la replicación y la disyunción de los cromosomas 01/01/2019 30/09/2022 MARIA NEUS COLOMINA GABARRELLA, JORDI TORRES ROSELL
Mecanismos moleculares de transacciones dependientes del complejo Smc5/6 sobre cromosomas eucarióticos 01/09/2022 31/08/2025 MARIA NEUS COLOMINA GABARRELLA, JORDI TORRES ROSELL
Mecanismos moleculares de activación de la sumo-ligasa NSE2 y de establecimiento de cohesión dependiente de Sumo (SUMECHS) 01/01/2013 31/12/2015 JORDI TORRES ROSELL
Disolución de uniones de DNA entre cromátides hermanas: la función del complejo de mantenimiento estructural de cromosomas Smc5/6 y su regulación por la vía SUMO 01/01/2010 31/12/2012 JORDI TORRES ROSELL
Thesis Year Direction
Analysis of ATP-Dependent Association of the Smc5/6 Complex with Chromatin 2022 Torres Rosell, Jordi
Molecular analysis of Smc5/6 dependent sumoylation and ubiquitination 2021 Torres Rosell, Jordi; Bellí, Gemma
The RING domain of Nse1: roles in Smc5/6 complex stability and genome integrity in human cells 2021 Jordi Torres Rosell; Neus Colomina Gabarrella
Coordinación de las actividades ATPasa y SUMO-ligasa en el complejo Smc5/6: implicaciones en reparación de cromosomas 2015 Jordi Torres Rosell i Neus Colomina Gabarrella
The role of the Smc5/6 complex and the Mms21 SUMO ligase in the maitenance of genomic integrity 2014 Torres Rosell, Jordi
A SUMO-dependent step during establishment of Sister Chromatid Cohesion 2013 Jordi Torres Rosell
Publications Year Authors Type
Cyclin D1-Cdk4 regulates neuronal activity through phosphorylation of GABAA receptors 2023 Pedraza N; Monserrat MV; Ferrezuelo F; Torres-Rosell J; Colomina N; Miguez-Cabello F; Párraga JP; Soto D; López-Merino E; García-Vilela C; Esteban JA; Egea J; Garí E. Article d'investigació
Ubiquitin proteomics identifies RNA polymerase I as a target of the Smc5/6 complex 2023 Ibars E; Codina-Fabra J; Bellí G; Casas C; Tarrés M; Solé-Soler R; Lorite NP; Ximénez-Embún P; Muñoz J; Colomina N; Torres-Rosell J. Article d'investigació
SUMO-SIM interactions: From structure to biological functions. 2022 Lascorz, J.; Codina Fabra, J.; Reverter, D.; Torres Rosell, J. Review
Antitumor Effects of Ral-GTPases Downregulation in Glioblastoma. 2022 Cemeli, T.; Guasch Vallés, M.; Ribes Santolaria, M.; Ibars, E.; Navaridas, R.; Dolcet, X.; Pedraza, N.; Colomina, N.; Torres Rosell, J.; Ferrezuelo, F.; Herreros, J.; Garí. E. Article d'investigació
Structural basis for the E3 ligase activity enhancement of yeast Nse2 by SUMO-interacting motifs. 2021 Varejã,o N.; Lascorz, J.; Codina Fabra, J.; Bellí, G.; Borràs Gas, H.; Torres Rosell, J.; Reverter, D.; Article d'investigació
Purified Smc5/6 Complex Exhibits DNA Substrate Recognition and Compaction 2020 Gutierrez Escribano, P.; Hormeño, S.; Madariaga Marcos, J.; Solé Soler, R.; O'Reilly, F.J.; Morris, K.; Aicart Ramos, C.; Aramayo, R.; Montoya, A.; Kramer, H.; Rappsilber, J.; Torres Rosell, J.; Moren Article d'investigació
Smc5/6, an atypical SMC complex with two RING-type subunits 2020 Solé Soler, R.; Torres Rosell, J. Review
Sumoylation of Smc5 promotes error-free bypass at damaged replication forks 2019 Zapatka M.; Pociño Merino I.; Heluani Gahete H.; Bermúdez López M.; Tarrés M.; Ibars E.; Solé Soler R.; Gutierrez Escribano P.; Apostolova S.; Casas C.; Aragon L.; Wellinger R.; Colomina N.; Torres Ro Article d'investigació
DNA activates the Nse2/Mms21 SUMO E3 ligase in the Smc5/6 complex. 2018 Varejao N; Ibars E; Lascorz J; Colomina N; Torres-Rosell J; Reverter D Article d'investigació
Analysis of SUMOylation in the RENT Complex by Fusion to a SUMO-Specific Protease Domain 2017 Colomina, C.; Guasch, C.; Torres-Rosell, J. Article d'investigació
Cytoplasmic cyclin D1 regulates cell invasion and metastasis through the phosphorylation of paxillin 2016 Fusté, N.P.; Fernández Hernández, R.; Cemeli, T.; Mirantes, C.; Pedraza, N.; Rafel, M.; Torres Rosell, J.; Colomina, N.; Ferrezuelo, F.; Dolcet, X.; Garí, E. Article d'investigació
Sgs1's roles in DNA end resection, HJ dissolution, and crossover suppression require a two-step SUMO regulation dependent on Smc5/6 2016 Bermúdez-López M, Villoria MT, Esteras M, Jarmuz A, Torres-Rosell J, Clemente-Blanco A, Aragon L. Article d'investigació
The Aurora-B-dependent NoCut checkpoint prevents damage of anaphase bridges after DNA replication stress 2016 Amaral N, Vendrell A, Funaya C, Idrissi FZ, Maier M, Kumar A, Neurohr G, Colomina N, Torres-Rosell J, Geli MI, Mendoza M. Article d'investigació
ATPase-Dependent Control of the Mms21 SUMO Ligase during DNA Repair 2015 Bermúdez-López, M; Pociño-Merino, I; Sánchez, H; Bueno, A; Guasch, C; Almedawar, S; Bru-Virgili, S; Garí, E; Wyman, C; Reverter, D; Colomina, N; Torres-Rosell, J. Article d'investigació
Smc5 flies solo. 2012 Torres-Rosell J; Losada A Review
A SUMO-Dependent Step during Establishment of Sister Chromatid Chohesion 2012 Almedawar S, Colomina N, Bermúdez-López M, Pociño-Merino I, Torres-Rosell J. Article d'investigació
The Smc5/6 complex is required for dissolution of DNA-mediated sister chromatid linkages 2010 Bermúdez-López M, Ceschia A, de Piccoli G, Colomina N, Pasero P, Aragón L, Torres-Rosell J. Article d'investigació
The unnamed complex: what do we know about Smc5-Smc6? 2009 De Piccoli G, Torres-Rosell J, Aragon L. Review
Smc5-Smc6 complex suppresses gross chromosomal rearrangements mediated by break-induced replications 2008 Hwang JY, Smith S, Ceschia A, Torres-Rosell J, Aragon L, Myung K. Article d'investigació
Can eukaryotic cells monitor the presence of unreplicated DNA? 2007 TORRES-ROSELL J, DE PICCOLI G, ARAGON L Review
Anaphase onset before complete DNA replication with intact checkpoint responses. 2007 Torres-Rosell J, De Piccoli G, Cordon-Preciado V, Farmer S, Jamuz A, Machin F, Pasero P, Lisby M, Haber JE, Aragon L Article d'investigació
The Smc5-Smc6 complex and SUMO modification of Rad52 regulates recombinational repair of double-strand breaks at the rDNA locus. 2007 Torres-Rosell J, Sunjevaric I, De Piccoli G, Sacher M, Eckert-Boulet N, Reid R, Jentsch S, Rothstein R, Aragon L, Lisby M Article d'investigació
Transcription of ribosomal genes can cause nondisjunction. 2006 Machin F, Torres-Rosell J, De Piccoli G, Carballo JA, Cha RS, Jarmuz A, Aragon L Article d'investigació
Smc5-Smc6 mediate DNA double-strand-break repair by promoting sister-chromatid recombination. 2006 De Piccoli G, Cortes-Ledesma F, Ira G, Torres-Rosell J, Uhle S, Farmer S, Hwang JY, Machin F, Ceschia A, McAleenan A, Cordon-Preciado V, Clemente-Blanco A, Vilella-Mitjana F, Ullal P, Jarmuz A, Leitao Article d'investigació
SMC5 and SMC6 genes are required for the segregation of repetitive chromosome regions 2005 Torres-Rosell J, Machin F, Farmer S, Jarmuz A, Eydmann T, Dalgaard JZ, Aragon L. Article d'investigació
Smc5-Smc6 complex preserves nucleolar integrity in S.cerevisiae. 2005 TORRES-ROSELL J, MACHIN F, ARAGON L Article d'investigació
Pkc1 and the upstream elements of the cell integrity pathway in Saccharomyces cerevisiae, Rom2 andMtl1, are required for cellular responses to oxidative stress 2005 Vilella F, Herrero E, Torres J, de la Torre MA. Article d'investigació
CDC14 and the Temporal Coordination between Mitotic Exit and Chromosome Segregation. 2005 TORRES-ROSELL J, MACHIN F, ARAGON L. Review
Spindle-independent condensation-mediated segregation of yeast ribosomal DNA in late anaphase 2005 Machin F, Torres-Rosell J, Jarmuz A, Aragon L. Article d'investigació
Condensin regulates rDNA silencing by modulating nucleolar Sir2p. 2004 Machin F, Paschos K, Jarmuz A, Torres-Rosell J, Pade C, Aragon L. Article d'investigació
Nucleolar Segregation Lags Behind the Rest of the Genome and Requires Cdc14p Activation by the FEAR Network. 2004 TORRES-ROSELL J, MACHIN F, JARMUZ A, ARAGON L. Article d'investigació
Regulation of the cell integrity pathway by rapamycin-sensitive Tor function in budding yeast 2002 Torres J, Di Como CJ, Herrero E, De la Torre-Ruiz MA. Article d'investigació
Sit4 is required for proper modulation of the biological functions mediated by Pkc1 and the cell integrity pathway in Sacharomyces cerevisiae 2002 De la Torre-Ruiz MA, Torres J, Ariño J, Herrero E. Article d'investigació